Evidence map›Paper›PMID 39179911›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2025

Pulsed-field ablation for atrial fibrillation without the use of fluoroscopy.

Nicholas O Palmeri, Daniel Alyesh, Madison Keith, Erin Greenhaw, Cooper Erickson, William Choe, Sri Sundaram

Abstract read
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In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Intracardiac Echocardiography during Invasive Electrophysiological Procedures: a Scientific Statement of the European Heart Rhythm Association of the ESC, and the European Association of Percutaneous Cardiovascular Interventions of the ESC.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Guideline
  2. Review
  3. Zero/Low-fluoroscopy pulsed-field ablation approach: a systematic review and meta-analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Review
  4. One year outcomes of a fluoroless pulsed field ablation approach for atrial fibrillation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
  5. Article
  6. When low is not low enough: zero-fluoroscopy atrial fibrillation ablation using the VARIPULSE™ pulsed field system-a prospective single-center study.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
  7. Safety and effectiveness of zero fluoroscopy procedures using a novel dual-energy ablation catheter.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Article
  8. Acute outcomes of cryoballoon vs. circular vs. pentaspline pulsed-field ablation catheters in combined pulmonary vein isolation and roof line ablation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Article
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  11. An approach to electroanatomical mapping with a pentaspline pulsed field catheter to guide atrial fibrillation ablation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nicholas O PalmeriCardiac Electrophysiology, South Denver Cardiology Associates, 1000 Southpark Drive, Littleton, CO, 80111, USA.
Daniel AlyeshCardiac Electrophysiology, South Denver Cardiology Associates, 1000 Southpark Drive, Littleton, CO, 80111, USA.
Madison KeithEP, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, North Chicago, IL, 60064, USA.
Erin GreenhawEP, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, North Chicago, IL, 60064, USA.
Cooper EricksonSouth Denver Cardiology Associates, 1000 Southpark Drive, Littleton, CO, 80111, USA.
William ChoeCardiac Electrophysiology, South Denver Cardiology Associates, 1000 Southpark Drive, Littleton, CO, 80111, USA.
Sri SundaramCardiac Electrophysiology, South Denver Cardiology Associates, 1000 Southpark Drive, Littleton, CO, 80111, USA. sris@southdenver.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPulsed-field ablation (PFA) and fluoroless ablation (FA) are emerging techniques in contemporary in electrophysiology. With widespread use of 3D electroanatomic mapping systems and advanced intracardiac echo (ICE) imaging, fluoroless ablation has become more widely adopted. However, with the importance of tissue contact for lesion durability, initial PFA has been used with fluoroscopic guidance, but both ICE and electroanatomic mapping make fluoroless PFA feasible. The objective of this study is to demonstrate that PFA can be done safely and effectively without fluoroscopy.

methodsAt a single center, consecutive patients undergoing ablation with a pentaspline PFA catheter using a fluoroless approach are described. The standard 3D anatomic map settings were adjusted with changes in interior and exterior projection, respiratory compensation, and interpolation. In addition, projection map lesions were used to confirm adequate circumferential ablation lesions. ICE was used extensively for wire guidance and evaluation of contact with tissue.

resultsBeginning on March 15, 2024, 50 consecutive subjects (19 female/31 male) aged 68.0 (± 13.7) underwent PFA ablation. The average CHA

conclusionIn comparison to the traditional PFA with fluoroscopy, this proof-of-concept study shows fluoroless PFA ablation can be performed safely and with similar acute success rates as with use of fluoroscopy.

Indexed as

Atrial FibrillationCatheter AblationAgedFemaleFluoroscopyHumansMaleMiddle AgedTreatment OutcomeAtrial fibrillationPulmonary vein isolationPulsed field ablation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.