Evidence map›Paper›PMID 39179877›Full record

ArticlePediatric research2026

Contrasting presentations of children with ADHD and subthreshold ADHD.

Lu He, Yan Zhao, Jin-Xin Gong, Lu Zhao, Zhou-Rui Ma, Qian-Wei Xiong, Shi-Zhong Cai, Xiang-Ming Yan

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Article in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Lu He *Department of Child and Adolescent Healthcare, Children's Hospital of Soochow University, Suzhou, China.
Yan Zhao *Department of Pediatrics, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Jin-Xin GongDepartment of Child and Adolescent Healthcare, Children's Hospital of Soochow University, Suzhou, China.
Lu ZhaoDepartment of Child and Adolescent Healthcare, Children's Hospital of Soochow University, Suzhou, China.
Zhou-Rui MaDepartment of Surgery, Children's Hospital of Soochow University, Suzhou, China.
Qian-Wei XiongSuzhou Key Laboratory of Children's Structural Deformities, Suzhou, China.
Shi-Zhong CaiDepartment of Child and Adolescent Healthcare, Children's Hospital of Soochow University, Suzhou, China. szcai@suda.edu.cn.
Xiang-Ming YanSuzhou Key Laboratory of Children's Structural Deformities, Suzhou, China. yxmsz2003@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to explore the differences and relationships in body composition, social function, and comorbidities between children with attention-deficit/hyperactivity disorder (ADHD) and subthreshold ADHD.

methodsA case-control study was conducted to analyze the differences between children with ADHD and subthreshold ADHD. Logistic regression models were used to analyze the factors influencing social functional impairments and comorbidities.

resultsChildren with ADHD and subthreshold ADHD had a higher fat mass index than healthy children (p < 0.05). The scores of all six social functional domains were higher in the subthreshold ADHD and ADHD groups than in the control group (p < 0.05). The prevalence of comorbidity was higher in children with subthreshold ADHD and ADHD compared to the control group (p < 0.05). Inattention and comorbid anxiety/depression increased the risk of functional impairments in children with ADHD (full syndrome/subthreshold), whereas a higher fat-free mass index reduced the risk. The severity of hyperactivity was associated with a higher risk of comorbidity in children with ADHD (full syndrome/subthreshold).

conclusionChildren with subthreshold ADHD and ADHD had more fat mass and higher rates of social functional impairments and comorbidities than healthy children. There were clinical correlations between body composition, social functional impairments, and comorbidities in ADHD. IMPACT: 1. Children with subthreshold ADHD and ADHD had higher fat mass levels than normal children. 2. The social function impairments and comorbidities of children with subthreshold ADHD were similar to those with ADHD. 3. Inattentiveness and anxiety/depression increased the risk of functional impairments in children with ADHD (full syndrome/subthreshold), while a higher fat-free mass index and skeletal muscle-to-body fat ratio reduced the risk.

Indexed as

Attention Deficit Disorder with HyperactivityAnxietyBody CompositionBody Mass IndexCase-Control StudiesChildComorbidityDepressionFemaleHumansLogistic ModelsMalePrevalenceRisk Factors

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.