Evidence map›Paper›PMID 39179736›Full record

ReviewBrain imaging and behavior2024

Altered cerebellar-cerebral dynamic functional connectivity in patients with pontine stroke: a resting-state fMRI study.

Xin Wang, Caihong Wang, Jingchun Liu, Jun Guo, Peifang Miao, Ying Wei, Yingying Wang, Zhen Li, Kaiyu Wang, Yong Zhang and 2 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Brain imaging and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xin Wang *Department of MRI, Key Laboratory for Functional Magnetic Resonance Imaging and Molecular Imaging of Henan Province, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe Dong Road, Erqi District, Zhengzhou, 450052, Henan, China.ORCID http://orcid.org/0009-0006-0007-9574
Caihong Wang *Department of MRI, Key Laboratory for Functional Magnetic Resonance Imaging and Molecular Imaging of Henan Province, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe Dong Road, Erqi District, Zhengzhou, 450052, Henan, China. fccwangch@zzu.edu.cn.
Jingchun LiuDepartment of Radiology, Tianjin Key Laboratory of Functional Imaging, Tianjin Medical University General Hospital, Tianjin, China.
Jun GuoDepartment of Radiology, Tianjin Huanhu Hospital, Tianjin, China.
Peifang MiaoDepartment of MRI, Key Laboratory for Functional Magnetic Resonance Imaging and Molecular Imaging of Henan Province, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe Dong Road, Erqi District, Zhengzhou, 450052, Henan, China.
Ying WeiDepartment of MRI, Key Laboratory for Functional Magnetic Resonance Imaging and Molecular Imaging of Henan Province, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe Dong Road, Erqi District, Zhengzhou, 450052, Henan, China.
Yingying WangDepartment of MRI, Key Laboratory for Functional Magnetic Resonance Imaging and Molecular Imaging of Henan Province, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe Dong Road, Erqi District, Zhengzhou, 450052, Henan, China.
Zhen LiDepartment of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Kaiyu WangGE Healthcare MR Research, Beijing, China.
Yong ZhangDepartment of MRI, Key Laboratory for Functional Magnetic Resonance Imaging and Molecular Imaging of Henan Province, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe Dong Road, Erqi District, Zhengzhou, 450052, Henan, China.
Jingliang ChengDepartment of MRI, Key Laboratory for Functional Magnetic Resonance Imaging and Molecular Imaging of Henan Province, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe Dong Road, Erqi District, Zhengzhou, 450052, Henan, China.
Cuiping RenDepartment of MRI, Key Laboratory for Functional Magnetic Resonance Imaging and Molecular Imaging of Henan Province, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe Dong Road, Erqi District, Zhengzhou, 450052, Henan, China. rcp810@sohu.com.ORCID http://orcid.org/0000-0003-2301-4280

Funding

National Natural Science Foundation of China 81871327Young Talents Promotion Program of Henan Province 2021HYTP012Young Teacher Cultivation Foundation of Zhengzhou University JC21854044
6 · The paper itself

Abstract

Potential changes in patterns of dynamic functional network connections at the cerebellar-cerebral level in pontine infarction (PI) patients remain unclear. The study aimed to investigate the abnormal patterns of dynamic functional connectivity (dFC) between the cerebellar subregions within networks and regions of the cerebral cortex in patients with PI. Forty-six chronic left pontine infarction (LPI), 32 chronic right pontine infarction (RPI), and 50 healthy controls (HCs) were recruited to undergo resting-state fMRI scans. Cerebellar-cerebral dFC was characterized using the sliding window method and seed-based connectivity analyses. Correlations between altered dFC values and clinical variables (The Rey Auditory Verbal Learning Test and Flanker task) in PI patients and healthy controls were investigated. Compared with HCs, the PI groups showed significantly aberrant cerebellar-cerebral dFC between cerebellar subregions within networks and supratentorial cerebral cortex, including executive, default-mode, and motor networks. Furthermore, Correlation analysis showed a decoupling between abnormal dFC and cognitive functions in PI patients. These findings indicate that PI patients are accompanied by damage to cerebellar subregions within networks and cerebellar-cerebral pathways, which may provide a potential target for treatment or an indication of therapeutic efficacy.

Indexed as

CerebellumCerebral CortexMagnetic Resonance ImagingNeural PathwaysPonsAdultAgedBrain MappingBrain Stem InfarctionsCognitionFemaleHumansMaleMiddle AgedNerve NetRestCerebellumDynamic functional connectivityfMRIFunctional networkPontine stroke

Identifiers

PMID39179736

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.