Evidence map›Paper›PMID 39179209›Full record

Trial reportJournal of substance use and addiction treatment2024

Harm reduction-focused behavioral activation for people who inject drugs: Mixed methods outcomes from a pilot open trial.

Catherine Paquette, Alexander Vierling, Louisa Kane, Paulina Linares Abrego, Katherine Benson, Elizabeth Jordan, Donald Baucom, William Zule, Stacey Daughters

Abstract readClinical Trial
In one paragraph

Trial report in Journal of substance use and addiction treatment, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Catherine PaquetteDuke University School of Medicine Department of Population Health Sciences, Durham, North Carolina, United States; University of North Carolina at Chapel Hill, United States. Electronic address: catherine.paquette@duke.edu.
Alexander VierlingUniversity of North Carolina at Chapel Hill, United States.
Louisa KaneUniversity of North Carolina at Chapel Hill, United States.
Paulina Linares AbregoUniversity of North Carolina at Chapel Hill, United States.
Katherine BensonUniversity of North Carolina at Chapel Hill, United States.
Elizabeth JordanEast Carolina University, United States.
Donald BaucomUniversity of North Carolina at Chapel Hill, United States.
William ZuleRTI International, United States.
Stacey DaughtersUniversity of North Carolina at Chapel Hill, United States.

Funding

Training on Research in Drug AbuseT32DA007244 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Regina M Carelli · 1990 to 2026
$7.6M
Behavioral Activation for Substance Use Among People Who Inject DrugsF31DA049457 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PAQUETTE, CATHERINE E. · 2019 to 2021
$112k
NIDA NIH HHS F31 DA049457NIDA NIH HHS T32 DA007244
6 · The paper itself

Abstract

introductionPeople who inject drugs (PWID) experience high rates of mental health problems and drug-related harms. Harm reduction-focused interventions aim to reduce harms associated with drug use and are an important approach for engaging people who are not seeking traditional abstinence-focused treatment. Yet, few studies to date have examined the effectiveness of harm reduction psychosocial treatment for drug use. We evaluated the outcomes of a harm reduction-focused behavioral activation (BA) intervention from pretreatment to a 1-month follow-up.

methodsA total of N = 23 PWID (65.2 % White; 52.2 % women; mean age 35.4 ± 7.8 years) were recruited from syringe services programs and n = 19 received the intervention via teletherapy. Assessment of study outcome measures occurred at pre- and posttreatment and a one-month follow-up.

resultsResults reflected post-intervention increases in behavioral activation and readiness to change drug use, as well as decreases in substance use, depression, and HIV risk behaviors. There were mixed outcomes on substance-related problems with increases at follow-up, possibly reflecting increased problem recognition.

conclusionsThese results suggest initial promise for the harm reduction-focused treatment. Additional research with randomized designs and larger sample sizes is needed, and more intensive treatment may be required to support sustained treatment gains in this population.

Indexed as

Behavior TherapyHarm ReductionSubstance Abuse, IntravenousAdultDepressionFemaleFollow-Up StudiesHIV InfectionsHumansMalePilot ProjectsRisk-TakingTreatment OutcomeBehavioral activationBehavior therapyHarm reductionIntravenous drug useLow-thresholdPeople who inject drugsTeletherapy

Identifiers

PMID39179209
PMCPMC11612634

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.