Evidence map›Paper›PMID 39179127›Full record

ArticleAmerican journal of ophthalmology2025

Laterality Targeting in Graded Inferior Rectus Tenotomy Corrects Lateral Incomitance of Hypertropia in Sagging Eye Syndrome.

Wei-Yu Lai, Joseph L Demer

Abstract readComparative Study
In one paragraph

Article in American journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Wei-Yu LaiFrom the Stein Eye Institute and Department of Ophthalmology University of California (W.Y.L., J.L.D.), Los Angeles, California, USA; Department of Ophthalmology (W.Y.L.), Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Joseph L DemerFrom the Stein Eye Institute and Department of Ophthalmology University of California (W.Y.L., J.L.D.), Los Angeles, California, USA; Department of Neurology (J.L.D.), University of California, Los Angeles, California, USA; Bioengineering Department (J.L.D.), University of California, Los Angeles, California, USA. Electronic address: jld@jsei.ucla.edu.

Funding

Vision Research Core at UCLAP30EY000331 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Xian-Jie Yang · 1985 to 2026
$16.8M
BIOMECHANICAL ANALYSIS IN STRABISMUS SURGERYR01EY008313 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JOSEPH Louis DEMER · 1991 to 2026
$15.0M
NEI NIH HHS P30 EY000331NEI NIH HHS R01 EY008313
6 · The paper itself

Abstract

purposeTo determine if laterally selective graded vertical rectus tenotomy (GVRT) of the inferior rectus (IR) can correct the lateral incomitance of hypertropia (HT) commonly encountered in sagging eye syndrome (SES), comparing it with inferior oblique (IO) recession.

designRetrospective comparative interventional clinical study.

methodsWe reviewed 73 consecutive patients undergoing GVRT of the IR for correction of horizontally incomitant HT due to SES from July 2012 to October 2023. Confounding diagnoses were excluded. Using topical anesthesia, GVRT was initiated from the nasal versus temporal side corresponding to greater HT, with dosing adjusted intraoperatively until cover testing in central gaze indicated orthotropia. We compared 8 cases of IO recession to 4 mm posterior and 3 mm lateral to the IR insertion.

resultsNasal GVRT was performed in 41 patients, and temporal GVRT on 32 patients. Mean nasal GVRT was 69 ± 15% (standard deviation) and mean temporal GVRT was 62 ± 17%. Mean HT in central gaze was reduced by nasal GVRT from 3.9 ± 1.7Δ to 0.3 ± 1.4Δ, and from 4.0 ± 1.6Δ to 0.2 ± 1.1Δ by temporal GVRT. Nasal GVRT corresponding to the side of the tenotomy had greater effect in contralateral gaze at 3.2 ± 2.2Δ than ipsilateral gaze at 2.1 ± 2.0Δ (P = .025), whereas temporal GVRT had greater effect in ipsilateral gaze at 4.9 ± 2.7D than contralateral gaze at 2.9 ± 2.9D (P = .0002). Inferior oblique recession in 8 patients reduced lateral incomitance from 13 ± 5.0Δ to 0.5 ± 1.4Δ (P < .0001).

conclusionNasal GVRT corrects about 1Δ and temporal GVRT 2Δ horizontal incomitance of HT, while IO recession corrects about 12.5Δ. Selection of GVRT laterality improves outcomes without additional risk or operating time.

Indexed as

Oculomotor MusclesStrabismusTenotomyVision, BinocularAdolescentAdultAgedChildEye MovementsFemaleHumansMaleMiddle AgedOphthalmologic Surgical ProceduresRetrospective StudiesYoung Adult

Identifiers

PMID39179127
PMCPMC12007455

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.