Evidence map›Paper›PMID 39178334›Full record

ArticleThe Journal of organic chemistry2024

Structure-Activity Relationship Studies of the Peptide Antibiotic Clovibactin.

Jackson E H Brunicardi, James H Griffin, Michael J Ferracane, Adam G Kreutzer, Jeramiah Small, Ana-Teresa Mendoza, Joseph W Ziller, James S Nowick

Erratum issuedAbstract read
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In one paragraph

Article in The Journal of organic chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Jackson E H BrunicardiDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.ORCID 0000-0002-3661-9476
James H GriffinDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.ORCID 0009-0004-9448-1526
Michael J FerracaneDepartment of Chemistry, University of Redlands, Redlands, California 92373, United States.
Adam G KreutzerDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.ORCID 0000-0002-9724-6298
Jeramiah SmallDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.
Ana-Teresa MendozaDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.ORCID 0009-0000-3799-1897
Joseph W ZillerDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.ORCID 0000-0001-7404-950X
James S NowickDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.ORCID 0000-0002-2273-1029

Funding

Synthesis and Evaluation of aza-Novo29 as an Antibiotic CandidateR21AI168966 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI NOWICK, JAMES S · 2022 to 2023
$401k
NIAID NIH HHS R21 AI168966
6 · The paper itself

Abstract

Our laboratory reported the chemical synthesis and stereochemical assignment of the recently discovered peptide antibiotic clovibactin. The current paper reports an improved, gram-scale synthesis of the amino acid building block Fmoc-(2

Indexed as

Anti-Bacterial AgentsCrystallography, X-RayMicrobial Sensitivity TestsModels, MolecularMolecular StructurePeptidesStereoisomerismStructure-Activity RelationshipAnti-Bacterial AgentsPeptides

Identifiers

PMID39178334
PMCPMC11382152

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.