Evidence map›Paper›PMID 39178328›Full record

ArticlePLoS neglected tropical diseases2024

Seroprevalence and risk factors for Q fever and Rift Valley fever in pastoralists and their livestock in Afar, Ethiopia: A One Health approach.

Regina Bina Oakley, Gizachew Gemechu, Ashenafi Gebregiorgis, Ayinalem Alemu, Jakob Zinsstag, Daniel Henry Paris, Rea Tschopp

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Article in PLoS neglected tropical diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Regina Bina OakleyDepartment of Medicine, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.ORCID 0000-0002-4085-8090
Gizachew GemechuOne Health Division, Armauer Hansen Research Institute, Addis Ababa, Ethiopia.
Ashenafi GebregiorgisOne Health Division, Armauer Hansen Research Institute, Addis Ababa, Ethiopia.
Ayinalem AlemuOne Health Division, Armauer Hansen Research Institute, Addis Ababa, Ethiopia.
Jakob ZinsstagUniversity of Basel, Basel, Switzerland.
Daniel Henry ParisDepartment of Medicine, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.
Rea TschoppUniversity of Basel, Basel, Switzerland.

Funding

Stanley Thomas Johnson Foundation 1053-KFU.S. Centers for Disease Control (CDC)
6 · The paper itself

Abstract

backgroundCoxiella burnetii, the causative agent of Q fever, and Rift Valley fever virus are two under-researched zoonotic pathogens in Ethiopia. Potential outbreaks of these diseases, in light of the high dependency of nomadic pastoralists on their livestock, poses a risk to both human and animal health in addition to risking the pastoralists livelihoods. Our study aimed to determine the seroprevalence and associated risk factors for Q fever and Rift Valley fever in pastoral communities in the Afar region of north-eastern Ethiopia. METHODOLOGY/PRINCIPAL

findingsThis cross-sectional study screened pastoralists (n = 323) and their livestock (n = 1377) for IgG antibodies to Coxiella burnetii and Rift Valley fever virus. A seroprevalence for Q fever of 25.0% (95%CI 18.6-32.6) was found in pastoralists and 34.3% (95%CI 27.9-41.3) in livestock overall; with 51.9% in goats (95%CI 44.9-58.8), 39.9% in sheep (95%CI 24.6-51.2), 16.3% in camels (95%CI 10.4-24.6) and 8.8% in cattle (95%CI 5.0-15.0). For Rift Valley fever the seroprevalence in pastoralists was 6.1% (95%CI 3.3-11.0) and 3.9% (95%CI 2.6-5.7) in livestock overall; cattle had the highest seroprevalence (8.3%, 95%CI 3.3-19.2), followed by goats (2.7%; 95%CI 1.4-5.1), sheep (2.5%; 95%CI 1.0-5.9) and camels (1.8%; 95%CI 0.4-6.9). Human Q fever seropositivity was found to be associated with goat abortions (OR = 2.11, 95%CI 1.18-3.78, p = 0.011), while Rift Valley fever seropositivity in livestock was found to be associated with cattle abortions (OR = 2.52, 95%CI 1.05-6.08, p = 0.039). CONCLUSIONS/SIGNIFICANCE: This study provides evidence for a notable exposure to both Q fever and Rift Valley fever in pastoralists and livestock in Afar. The outbreak potential of these pathogens warrants ongoing integrated human and animal surveillance requiring close collaboration of the human and animal health sectors with community representatives following a One Health approach.

Indexed as

Coxiella burnetiiGoatsLivestockQ FeverRift Valley FeverRift Valley fever virusAdolescentAdultAnimalsAntibodies, BacterialAntibodies, ViralCamelusCattleCattle DiseasesCross-Sectional StudiesEthiopiaAntibodies, BacterialAntibodies, ViralImmunoglobulin G

Identifiers

PMID39178328
PMCPMC11376510

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