Evidence map›Paper›PMID 39178253›Full record

ArticleScience advances2024

Lung cell transplantation for pulmonary fibrosis.

Irit Milman Krentsis, Yangxi Zheng, Chava Rosen, Sarah Y Shin, Christa Blagdon, Einav Shoshan, Yuan Qi, Jing Wang, Sandeep K Yadav, Esther Bachar Lustig and 4 more

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Murine models of pulmonary fibrosis: mechanisms, limitations and translational insights.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  7. Article
  8. Engineering function in lung biology: integrating imaging, regenerative constructs, and functional biodesign.American journal of physiology. Lung cellular and molecular physiology · 2026
    Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. From Epithelium to Therapy: Transitional Cells in Lung Fibrosis.American journal of respiratory cell and molecular biology · 2025
    Review
  15. Article
  16. Lung stem cells and respiratory epithelial chimerism in transplantation.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Irit Milman KrentsisDepartment of Stem Cell Transplantation and Cell Therapy, MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0003-2127-1347
Yangxi ZhengDepartment of Stem Cell Transplantation and Cell Therapy, MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0003-3349-7124
Chava RosenDepartment of Stem Cell Transplantation and Cell Therapy, MD Anderson Cancer Center, Houston, TX, USA.
Sarah Y ShinDepartment of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Christa BlagdonDepartment of Stem Cell Transplantation and Cell Therapy, MD Anderson Cancer Center, Houston, TX, USA.ORCID 0009-0008-3177-2608
Einav ShoshanDepartment of Stem Cell Transplantation and Cell Therapy, MD Anderson Cancer Center, Houston, TX, USA.
Yuan QiDepartment of Bioinformatics and Computational Biology, MD Anderson Cancer, Houston, TX, USA.ORCID 0000-0001-9718-7593
Jing WangDepartment of Bioinformatics and Computational Biology, MD Anderson Cancer, Houston, TX, USA.ORCID 0000-0002-5398-0802
Sandeep K YadavDepartment of Stem Cell Transplantation and Cell Therapy, MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0001-6999-040X
Esther Bachar LustigDepartment of Stem Cell Transplantation and Cell Therapy, MD Anderson Cancer Center, Houston, TX, USA.
Elias ShetzenDepartment of Stem Cell Transplantation and Cell Therapy, MD Anderson Cancer Center, Houston, TX, USA.
Burton F DickeyDepartment of Pulmonary Medicine, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0002-4780-1847
Harry Karmouty-QuintanaDepartment of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, Houston, TX, USA.ORCID 0000-0003-4753-9823
Yair ReisnerDepartment of Stem Cell Transplantation and Cell Therapy, MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0002-3354-6945

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
Controlling the core airway mucin secretion machinery to prevent pathophysiologyR01HL129795 · NHLBI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DICKEY, BURTON F · 2015 to 2023
$3.8M
Sineoculis Homeobox Homolog 1 (Six1) in Pulmonary FibrosisR01HL157100 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KARMOUTY-QUINTANA, HARRY · 2021 to 2025
$2.8M
3'UTR Shortening In Pulmonary Vascular DiseaseR01HL138510 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KARMOUTY-QUINTANA, HARRY · 2017 to 2021
$2.3M
NCI NIH HHS P30 CA016672NHLBI NIH HHS R01 HL129795NHLBI NIH HHS R01 HL138510NHLBI NIH HHS R01 HL157100
6 · The paper itself

Abstract

Idiopathic pulmonary fibrosis is a major cause of death with few treatment options. Here, we demonstrate the therapeutic efficacy for lung fibrosis of adult lung cell transplantation using a single-cell suspension of the entire lung in two distinct mouse systems: bleomycin treatment and mice lacking telomeric repeat-binding factor 1 expression in alveolar type 2 (AT2) cells (

Indexed as

Disease Models, AnimalAnimalsBleomycinIdiopathic Pulmonary FibrosisLungLung TransplantationMicePulmonary FibrosisBleomycin

Identifiers

PMID39178253
PMCPMC11343030

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.