Evidence map›Paper›PMID 39178194›Full record

ArticleEmerging microbes & infections2024

A retrospective survey on the effectiveness of vaccines administered to individuals in China with regard to inactivated COVID-19 vaccines, Ad5-nCoV and/or aerosolized Ad5-nCoV.

Zhe Zhang, Xiang-Yang Chi, Guan-Ying Zhang, Zhang Zhang, Song-He Lu, Meng-Jing Li, Liang-Jun Li, Jin-Long Zhang, Fang-Ze Shao, Yue Zhang and 2 more

Abstract read
In one paragraph

Article in Emerging microbes & infections, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zhe ZhangLaboratory of Advanced Biotechnology, Beijing Institute of Biotechnology, Beijing, People's Republic of China.ORCID 0000-0002-9303-8221
Xiang-Yang ChiLaboratory of Advanced Biotechnology, Beijing Institute of Biotechnology, Beijing, People's Republic of China.ORCID 0000-0002-0580-5997
Guan-Ying ZhangLaboratory of Advanced Biotechnology, Beijing Institute of Biotechnology, Beijing, People's Republic of China.ORCID 0000-0003-3372-3355
Zhang ZhangLaboratory of Advanced Biotechnology, Beijing Institute of Biotechnology, Beijing, People's Republic of China.ORCID 0000-0001-6088-2293
Song-He LuThe Fourth Military Medical University, Xi'an, People's Republic of China.
Meng-Jing LiThe Eastern Theater Navy, Ningbo, People's Republic of China.
Liang-Jun LiThe Chinese People's Armed Police Force (PAP) Shanghai Corps, Shanghai, People's Republic of China.
Jin-Long ZhangLaboratory of Advanced Biotechnology, Beijing Institute of Biotechnology, Beijing, People's Republic of China.ORCID 0000-0001-9427-2645
Fang-Ze ShaoLaboratory of Advanced Biotechnology, Beijing Institute of Biotechnology, Beijing, People's Republic of China.
Yue ZhangLaboratory of Advanced Biotechnology, Beijing Institute of Biotechnology, Beijing, People's Republic of China.
Li-Hua HouLaboratory of Advanced Biotechnology, Beijing Institute of Biotechnology, Beijing, People's Republic of China.ORCID 0000-0001-7366-8974
Wei ChenLaboratory of Advanced Biotechnology, Beijing Institute of Biotechnology, Beijing, People's Republic of China.ORCID 0000-0001-5805-2469

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We administered a questionnaire to participants who received different vaccination regimens to evaluate the effectiveness of Ad5-vectored COVID-19 vaccines. The results showed that administration of intramuscular Ad5-nCoV provided 21.32% more protection against SARS-CoV-2 infection than that of the inactivated COVID-19 vaccine in people who had received only one type of COVID-19 vaccine. Furthermore, aerosolized Ad5-nCoV exhibited good protection, whether it was administered as a homologous booster to people vaccinated with the intramuscular Ad5-nCoV or as a heterologous booster to people vaccinated with inactivated COVID-19 vaccines. Our research indicates that Ad5-nCoV is an effective booster. This finding supports the future selection of COVID-19 immunization strategies.

Indexed as

COVID-19COVID-19 VaccinesSARS-CoV-2Vaccines, InactivatedAdultAerosolsAgedAntibodies, ViralChinaFemaleHumansImmunization, SecondaryMaleMiddle AgedRetrospective StudiesSurveys and QuestionnairesAerosolsAntibodies, ViralCOVID-19 VaccinesVaccines, Inactivatedaerosolized Ad5-nCoVboosterCOVID-19mucosalrelative effectiveness

Identifiers

PMID39178194
PMCPMC11370693

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.