Evidence map›Paper›PMID 39177925›Full record

ArticleJournal of artificial organs : the official journal of the Japanese Society for Artificial Organs2025

Computational fluid dynamics simulating of the FDA benchmark blood pump with different coefficient sets and scaler shear stress models used in the power-law hemolysis model.

Ahmet Onder, Omer Incebay, Rafet Yapici

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Article in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Ahmet OnderTechnical Sciences Vocational School, Mechanical and Metal Technologies Department, Konya Technical University, Konya, Turkey. aonder@ktun.edu.tr.ORCID http://orcid.org/0000-0001-8419-6896
Omer IncebayFaculty of Engineering and Natural Science, Mechanical Engineering Department, Konya Technical University, Konya, Turkey.
Rafet YapiciFaculty of Engineering and Natural Science, Mechanical Engineering Department, Konya Technical University, Konya, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemolysis is the most important issue to consider in the design and optimization of blood-contacting devices. Although the use of Computational Fluid Dynamics (CFD) in hemolysis prediction studies provides convenience and has promising potential, it is an extremely challenging process. Hemolysis predictions with CFD depend on the mesh, implementation method, coefficient set, and scalar-shear-stress model. To this end, an attempt was made to find the combination that would provide the most accurate result in hemolysis prediction with the commonly cited power-law based hemolysis model. In the hemolysis predictions conducted using CFD on the Food and Drug Administration (FDA) benchmark blood pump, 3 different scalar-shear-stress models, and 5 different coefficient sets with the power-law based hemolysis model were used. Also, a mesh independence test based on hemolysis and pressure head was performed. The pressure head results of CFD simulations were compared with published pressure head of the FDA benchmark blood pump and a good agreement was observed. In addition, results of CFD-hemolysis predictions which are conducted with scalar-shear-stress model and coefficient set combinations were compared with experimental hemolysis data at three operating conditions such as 6-7 L/min flow rates at 3500 rpm rotational speeds and 6 L/min at 2500 rpm. One of the combinations of the scalar-shear-stress model and the coefficient set was found to be within the error limits of the experimental measurements, while all other combinations overestimated hemolysis.

Indexed as

Computer SimulationHeart-Assist DevicesHemolysisHydrodynamicsEquipment DesignHumansModels, CardiovascularStress, MechanicalUnited StatesUnited States Food and Drug AdministrationCentrifugal blood pumpCFDHemolysisScalar shear stress

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.