Evidence map›Paper›PMID 39177856›Full record

ArticleEuropean radiology2025

Ligamentum teres lesions are associated with compositional and structural hip cartilage degenerative change: region-specific cartilage degeneration.

Zehra Akkaya, Paula J Giesler, Koren E Roach, Gabby B Joseph, Charles E McCulloch, Upasana U Bharadwaj, Richard B Souza, Sharmila Majumdar, Thomas M Link

Abstract read
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Article in European radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Fossa-Foveolar Mismatch Is Highest in Dysplastic Hips and During External Rotation.Arthroscopy, sports medicine, and rehabilitation · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zehra AkkayaDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA. zehraakkaya@gmail.com.ORCID http://orcid.org/0000-0002-6483-3381
Paula J GieslerDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.
Koren E RoachDepartment of Biomedical Engineering, University of Calgary, Calgary, AB, Canada.
Gabby B JosephDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.
Charles E McCullochDepartment of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.
Upasana U BharadwajDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.
Richard B SouzaDepartment of Physical Therapy and Rehabilitation Science, University of California, San Francisco, CA, USA.
Sharmila MajumdarDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.
Thomas M LinkDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.

Funding

Structural, Biochemical and Functional Connectivity in Osteoarthritis using Quantitative Magnetic Resonance Imaging and Skeletal BiomechanicsR01AR069006 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MAJUMDAR, SHARMILA, SOUZA, RICHARD BRIAN · 2016 to 2025
$7.2M
Understanding the mechanisms by which weight change affects progression of knee osteoarthritis in obese and overweight individuals: An analysis of the Osteoarthritis Initiative DatasetR01AR078917 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GABRIELLE JOSEPH, THOMAS M LINK · 2021 to 2026
$3.4M
NIAMS NIH HHS R01 AR078917NIH HHS R01AR069006
6 · The paper itself

Abstract

objectivesTo investigate the association between magnetic resonance imaging (MRI)-based ligamentum teres lesions (LTL) and structural hip degeneration.

methodsBilateral 3-T hip MRIs of participants (n = 93 [36 men]; mean age ( ± SD) 51 years ± 15.4) recruited from the community and the orthopedic clinic of a single medical center were included. Clinical and imaging data acquired included hip disability and osteoarthritis outcome scores, semi-quantitative scoring of hip osteoarthritis on MRI (SHOMRI) scores on fluid-sensitive sequences, and cartilage T

resultsIn 82 (46.1%) hips, no pain was documented; 118 (63.4%) and 68 (36.6%) hips were graded as KL-grade ≤ 1 and ≥ 2, respectively. Compared to MRI-LT score = 0 (normal), score = 4 (complete tear) revealed significantly worse subchondral bony degenerative changes for bone marrow lesions (SHOMRI-BML) and subchondral cysts (SHOMRI-sc) (p < 0.001, p = 0.015, respectively). Global acetabular T

conclusionMRI abnormalities of LT are associated with worse SHOMRI-sc/BML scores, indicative of hip osteoarthritis and higher T CLINICAL RELEVANCE STATEMENT: Abnormal ligamentum teres findings identified via MRI are associated with structural degenerative changes of the hip joint and alterations in acetabular and femoral cartilage compositions show spatial differences in relation to LTL. KEY POINTS: The clinical significance of common ligamentum teres lesions (LTL) on MRI is not well understood. LTL identified by an MRI-based scoring system is associated with worse biomarkers, indicating more advanced degenerative hip changes. Effusion-synovitis signal at pulvinar, shallow fovea capitis, and foveal osteophytes are associated with LTL on imaging.

Indexed as

Cartilage, ArticularHip JointMagnetic Resonance ImagingOsteoarthritis, HipRound LigamentsAdultAgedFemaleHumansMaleMiddle AgedHipLigamentum teresOsteoarthritisQuantitative MRI

Identifiers

PMID39177856

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.