Evidence map›Paper›PMID 39177809›Full record

Trial reportPsychopharmacology2025

Attentional bias to alcohol-related cues: effects of menstrual cycle phase and sex differences.

Annie K Griffith, Michelle M Martel, Mark T Fillmore

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Psychopharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Annie K GriffithDepartment of Psychology, University of Kentucky College of Arts and Sciences, 110 Kastle Hall, 40506-0044, Lexington, KY, USA.
Michelle M MartelDepartment of Psychology, University of Kentucky College of Arts and Sciences, 110 Kastle Hall, 40506-0044, Lexington, KY, USA.
Mark T FillmoreDepartment of Psychology, University of Kentucky College of Arts and Sciences, 110 Kastle Hall, 40506-0044, Lexington, KY, USA. fillmore@uky.edu.

Funding

Estradiol Effects on Behavioral and Reward Sensitivity to Alcohol across the Menstrual CycleR01AA027990 · NIAAA · UNIVERSITY OF KENTUCKY · PI FILLMORE, MARK T, MARTEL, MICHELLE M · 2020 to 2024
$2.6M
Interdisciplinary Training in Alcohol ResearchT32AA027488 · NIAAA · UNIVERSITY OF KENTUCKY · PI Mark T Fillmore, Mark A Prendergast · 2019 to 2026
$2.0M
NIAAA NIH HHS R01 AA027990NIAAA NIH HHS T32 AA027488
6 · The paper itself

Abstract

rationaleA recent study by our group found that women displayed greater attentional bias to alcohol-related cues during the late versus early follicular phase in both sober and intoxicated states, suggesting a greater risk of excessive drinking among women during this phase. Changes in attentional bias as a function of menstrual cycle phase raise questions about potential sex differences in the relative consistency by which women and men display attentional bias to alcohol over time.

objectivesThe present study tested sex differences in attentional bias to alcohol by comparing the change in women's attentional bias from early to late follicular phase to that observed in men over the same period.

methodsTwenty-five men and 25 women aged 21-32 participated in a placebo-controlled study examining sex differences in the rewarding properties of alcohol. Participants completed measures of attentional bias to alcohol-related cues during two sessions following both 0.6 g/kg alcohol and placebo. Test sessions occurred one week apart, and for female participants coincided with the early and late follicular phases.

resultsMen consistently displayed attentional bias to alcohol-related cues across sessions under both doses. By contrast, women showed attentional bias only during the late follicular phase, at a magnitude greater than that observed in men, and persistent under both doses.

conclusionsThese findings highlight the potential role of sex and menstrual cycle phase in sensitizing drinkers to rewarding properties of alcohol-related cues. Men's motivation to drink may remain relatively consistent, whereas women may be most motivated during the late follicular phase.

Indexed as

Alcohol DrinkingAttentional BiasCuesEthanolMenstrual CycleAdultAttentionFemaleFollicular PhaseHumansMaleRewardSex FactorsYoung AdultEthanolAlcoholAttentional biasEstradiolFollicular phaseMenstrual cycleRewardSex differences

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.