Evidence map›Paper›PMID 39177336›Full record

ArticleJournal of the American Geriatrics Society2024

Impact of federal antipsychotic use policy in nursing homes on new diagnoses for approved indications in dementia residents.

Theresa I Shireman, Neto Coulibaly, Tingting Zhang, Andrew R Zullo, Lauren B Gerlach, Antoinette B Coe, Lori A Daiello, Derrick Lo, Julie P W Bynum

Abstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trajectories of Medication Use Prior to Death in US Nursing Home Residents With Dementia.Journal of the American Medical Directors Association · 2026
    Article
  2. Impact of national partnership to improve dementia care on antipsychotic use duration for dementia residents in nursing homes.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Theresa I ShiremanCenter for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, Rhode Island, USA.ORCID https://orcid.org/0000-0001-6846-8783
Neto CoulibalyDepartment of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, Rhode Island, USA.
Tingting ZhangCenter for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, Rhode Island, USA.
Andrew R ZulloCenter for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, Rhode Island, USA.ORCID https://orcid.org/0000-0003-1673-4570
Lauren B GerlachInstitute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0003-1943-0150
Antoinette B CoeInstitute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0002-5723-0443
Lori A DaielloCenter for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, Rhode Island, USA.
Derrick LoCenter for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, Rhode Island, USA.
Julie P W BynumInstitute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0003-1481-4462

Funding

VARIATIONS IN LIFE'S FINAL CHAPTERP01AG027296 · NIA · BROWN UNIVERSITY · PI AMAL N. TRIVEDI · 2007 to 2026
$38.9M
Clinically Significant Drug Interactions among Nursing Home Residents with ADRDR01AG077620 · NIA · BROWN UNIVERSITY · PI Andrew Reis Zullo · 2022 to 2026
$3.5M
Medications and the Risk of Motor Vehicle Crashes in Older AdultsR01AG065722 · NIA · BROWN UNIVERSITY · PI ZULLO, ANDREW REIS · 2020 to 2023
$2.1M
Medicating distress: Use of psychotropic medications among patients with dementia receiving hospice careK23AG066864 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GERLACH, LAUREN BETH · 2021 to 2025
$1.0M
Improving Medication Use and Outcomes in Older Adults with Dementia after Hospitalization: Effectiveness of Medicare ProgramsK08AG071856 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COE, ANTOINETTE BARTOLOTTA · 2021 to 2024
$620k
NIA NIH HHS K08 AG071856NIA NIH HHS K23 AG066864NIA NIH HHS K23AG066864NIA NIH HHS P01 AG027296NIA NIH HHS R01 AG065722NIA NIH HHS R01AG065722NIA NIH HHS R01 AG077620NIA NIH HHS R01AG077620
6 · The paper itself

Abstract

backgroundFederal policies targeting antipsychotic use among nursing home (NH) residents may have increased reporting of diagnoses for approved uses, including schizophrenia, Tourette's syndrome, and Huntington's Disease (called "exclusionary diagnoses" because they exclude residents from the antipsychotic quality metric). We assessed changes in new exclusionary diagnoses among long-stay NH admissions specifically with dementia following federal policies.

methodsRetrospective, quarterly, interrupted time-series analysis (2009-2018) of new long-stay NH residents with dementia and no exclusionary diagnoses reported before NH admission. The National Partnership and the addition of facility level antipsychotic use to the Five Star Quality Rating system were key time exposures. Outcome was quarterly facility level predicted percentage of exclusionary diagnoses within 2 years of admission stratified by NH characteristics.

resultsFor 264,095 long-stay admissions, mean percentage of new exclusionary diagnoses was 2.2% before the Partnership. After the Partnership, there was an unadjusted increase in the percentage over time (slope change, 0.044, p = 0.018), but the percentage never exceeded 2.9%. The Partnership contributed to a one-time decrease in diagnoses in NHs with an intermediate percentage of Black residents (-1.29%, p = 0.004). Before the Partnership, diagnoses were increasing among not-for-profit relative to for-profit NHs (0.044; p = 0.012), but after the Partnership, the pattern reversed. For-profit NHs saw an increase (+0.034, p = 0.002); not-for-profit NHs experienced a decrease (-0.014, p = 0.039). Quality Rating modifications had no significant effect.

conclusionsExclusionary diagnosis reporting among long-stay NH residents with dementia, the group most at risk from antipsychotics, did not increase in response to federal policies. Evaluation of reasons for the observed increase in exclusionary diagnoses among non-dementia NH residents is warranted along with continued attention to how to incentivize the appropriate use of medications in residents with dementia that is crucial for high-quality NH care.

Indexed as

Antipsychotic AgentsDementiaInterrupted Time Series AnalysisNursing HomesAgedAged, 80 and overFemaleHomes for the AgedHumansMaleRetrospective StudiesUnited StatesAntipsychotic Agentsantipsychoticsdementiaexclusionary diagnoseshealth policyinterrupted time‐series analysisnursing homes

Identifiers

PMID39177336
PMCPMC11637966

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.