Evidence map›Paper›PMID 39177307›Full record

ArticleeLife2024

Inhibitors of the small membrane (M) protein viroporin prevent Zika virus infection.

Emma Brown, Gemma Swinscoe, Daniella A Lefteri, Ravi Singh, Amy Moran, Rebecca F Thompson, Daniel Maskell, Hannah Beaumont, Matthew J Bentham, Claire Donald and 7 more

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. AlphaFold Prediction of Protein-Protein Interactions in theInternational journal of molecular sciences · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Emma BrownAstbury Centre for Structural and Molecular Biology, University of Leeds, Leeds, United Kingdom.
Gemma SwinscoeAstbury Centre for Structural and Molecular Biology, University of Leeds, Leeds, United Kingdom.
Daniella A LefteriLeeds Institute of Medical Research, School of Medicine, Faculty of Medicine and Health, University of Leeds, St James' University Hospital, Leeds, United Kingdom.ORCID https://orcid.org/0000-0002-9985-4254
Ravi SinghAstbury Centre for Structural and Molecular Biology, University of Leeds, Leeds, United Kingdom.ORCID https://orcid.org/0000-0003-4344-4085
Amy MoranAstbury Centre for Structural and Molecular Biology, University of Leeds, Leeds, United Kingdom.
Rebecca F ThompsonAstbury Centre for Structural and Molecular Biology, University of Leeds, Leeds, United Kingdom.
Daniel MaskellAstbury Centre for Structural and Molecular Biology, University of Leeds, Leeds, United Kingdom.
Hannah BeaumontAstbury Centre for Structural and Molecular Biology, University of Leeds, Leeds, United Kingdom.
Matthew J BenthamAstbury Centre for Structural and Molecular Biology, University of Leeds, Leeds, United Kingdom.
Claire DonaldMRC and University of Glasgow Centre for Virus Research, Sir Michael Stoker Building, Glasgow, United Kingdom.ORCID https://orcid.org/0000-0002-4370-0707
Alain KohlMRC and University of Glasgow Centre for Virus Research, Sir Michael Stoker Building, Glasgow, United Kingdom.
Andrew MacdonaldAstbury Centre for Structural and Molecular Biology, University of Leeds, Leeds, United Kingdom.
Neil RansonAstbury Centre for Structural and Molecular Biology, University of Leeds, Leeds, United Kingdom.
Richard Foster *Astbury Centre for Structural and Molecular Biology, University of Leeds, Leeds, United Kingdom.
Clive S McKimmie *Leeds Institute of Medical Research, School of Medicine, Faculty of Medicine and Health, University of Leeds, St James' University Hospital, Leeds, United Kingdom.
Antreas C Kalli *Astbury Centre for Structural and Molecular Biology, University of Leeds, Leeds, United Kingdom.ORCID https://orcid.org/0000-0001-7156-9403
Stephen GriffinAstbury Centre for Structural and Molecular Biology, University of Leeds, Leeds, United Kingdom.ORCID https://orcid.org/0000-0002-7233-5243

Funding

Medical Research Council G0700124Medical Research Council MC_UU_12014/8Medical Research Council MR/N017552/1Medical Research Council MR/T016205/1UK Research and Innovation Impact Acceleration Account ( IAA)UK Research and Innovation Impact Acceleration Account (IAA)University of Leeds LIMR Studentship
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antiviral AgentsZika VirusZika Virus InfectionAnimalsChlorocebus aethiopsHumansMolecular Dynamics SimulationRimantadineVero CellsViral Matrix ProteinsViroporin ProteinsAntiviral AgentsRimantadineViral Matrix ProteinsViroporin ProteinsFlavivirusinfectious diseaseion channelmicrobiologymouserimantadineviroporinvirus entryvirusesZika

Identifiers

PMID39177307
PMCPMC11449487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.