Evidence map›Paper›PMID 39177016›Full record

ArticleCancer medicine2024

A qualitative exploration of the pathway to diagnosis and treatment of cutaneous squamous cell carcinoma of the head and neck with perineural spread.

Poorva Pradhan, Ke Zoe Wan, Li Chan, Tsu-Hui Hubert Low, Raymond Wu, Jenny H Lee, Carsten E Palme, Jonathan R Clark, Rebecca L Venchiarutti

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Poorva PradhanDepartment of Head and Neck Surgery, Chris O'Brien Lifehouse, Camperdown, New South Wales, Australia.ORCID 0000-0001-9308-5717
Ke Zoe WanSydney School of Public Health, The University of Sydney, Sydney, New South Wales, Australia.
Li ChanDepartment of Radiation Oncology, St George Hospital, Kogarah, New South Wales, Australia.
Tsu-Hui Hubert LowDepartment of Head and Neck Surgery, Chris O'Brien Lifehouse, Camperdown, New South Wales, Australia.
Raymond WuCentral Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.
Jenny H LeeDepartment of Medical Oncology, Chris O'Brien Lifehouse, Camperdown, New South Wales, Australia.
Carsten E PalmeDepartment of Head and Neck Surgery, Chris O'Brien Lifehouse, Camperdown, New South Wales, Australia.
Jonathan R ClarkDepartment of Head and Neck Surgery, Chris O'Brien Lifehouse, Camperdown, New South Wales, Australia.
Rebecca L VenchiaruttiDepartment of Head and Neck Surgery, Chris O'Brien Lifehouse, Camperdown, New South Wales, Australia.ORCID 0000-0001-6493-7933

Funding

Cancer Institute NSW
6 · The paper itself

Abstract

backgroundPerineural spread (PNS) is associated with a poor prognosis in cutaneous squamous cell carcinoma of the head and neck (cSCCHN). Hence, investigating facilitators and barriers of early diagnosis and treatment of PNS in cSCCHN may improve outcomes.

methodsPatients were recruited from an institutional database. Semi-structured interviews were conducted according to the Model of Pathways to Treatment. Thematic analysis was based on the four main intervals in the framework using a data-driven analytical method.

resultsSeventeen participants were interviewed. Facilitators included patients' past experiences, symptom progression, trust in healthcare professionals (HCPs), and capacity to leverage relationships. Barriers included difficult diagnoses, limited access to cancer services, lack of care coordination, and lack of awareness of PNS among primary health care providers.

conclusionThese findings emphasise the complexity early diagnosis and treatment of PNS. Interventions like clinical practice guidelines, education for HCPs, and telehealth could facilitate timely detection and management.

Indexed as

Head and Neck NeoplasmsSkin NeoplasmsAgedAged, 80 and overCarcinoma, Squamous CellFemaleHumansMaleMiddle AgedQualitative ResearchSquamous Cell Carcinoma of Head and Neckcutaneous squamous cell carcinomahead and neckmodels of pathways to treatmentneoplasmPerineural spread

Identifiers

PMID39177016
PMCPMC11342044

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.