Evidence map›Paper›PMID 39176291›Full record

ArticleCurrent urology2024

Which characteristics are associated with changes in medication status for lower urinary tract symptoms among patients with prostate cancer receiving external beam radiotherapy?

Yuki Kyoda, Kohei Hashimoto, Atsushi Takahashi, Takeshi Maehana, Kimihito Tachikawa, Takashi Muranaka, Shuichi Kato, Tomoyo Kurisu, Fumimasa Fukuta, Takahiro Kirisawa and 5 more

Abstract read
In one paragraph

Article in Current urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Impact of Hormonal and Radiation Therapy on Bladder Outlet Obstruction in High-Risk Localized Prostate Cancer: A Prospective Pressure-Flow Study.International journal of urology : official journal of the Japanese Urological Association · 2026
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yuki KyodaDepartment of Urology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Kohei HashimotoDepartment of Urology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Atsushi TakahashiDepartment of Urology, Hakodate Goryoukaku Hospital, Hakodate, Japan.
Takeshi MaehanaDepartment of Urology, Muroran City General Hospital, Muroran, Japan.
Kimihito TachikawaDepartment of Urology, NTT-East Sapporo Hospital, Sapporo, Japan.
Takashi MuranakaDepartment of Urology, Sunagawa City Medical Center, Sunagawa, Japan.
Shuichi KatoDepartment of Urology, Oji General Hospital, Tomakomai, Japan.
Tomoyo KurisuDepartment of Urology, Steel Memorial Muroran Hospital, Muroran, Japan.
Fumimasa FukutaDepartment of Urology, Steel Memorial Muroran Hospital, Muroran, Japan.
Takahiro KirisawaDepartment of Urology, Obihiro Kyokai Hospital, Obihiro, Japan.
Manabu OkadaDepartment of Urology, Obihiro Kyokai Hospital, Obihiro, Japan.
Ko KobayashiDepartment of Urology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Toshiaki TanakaDepartment of Urology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Shiro HinotsuDepartment of Medical Statistics, Sapporo Medical University School of Medicine, Sapporo, Japan.
Naoya MasumoriDepartment of Urology, Sapporo Medical University School of Medicine, Sapporo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We clarified the predictive factors for changes in the status of medications for lower urinary tract symptoms (LUTS) 2 years after local radiotherapy for nonmetastatic prostate cancer. Materials and methods: We retrospectively included patients who underwent local external radiotherapy for nonmetastatic prostate cancer in 8 institutions between April 2001 and March 2016. Patients were divided into the medication and no-medication group based on the use of drugs for LUTS before radiotherapy. We defined improvement of LUTS as when the patient did not require medication for LUTS at 24 months after radiotherapy in the medication group and as deterioration when medication was required in the no-medication group. Logistic regression analysis was used to evaluate predictive factors for changes in medication status. Results: Altogether, 505 patients were divided into a no-medication group (n = 352) and a medication group (n = 153). The number of patients with deterioration and improvement in LUTS was 49 (14%) and 36 (23%), respectively. In the multivariate analysis, the predictive variables for deterioration were the International Prostate Symptom Score (≥8; odds ratio [OR], 2.21; Conclusions: These predictive factors for changes in the status of medications for LUTS at 2 years after external radiotherapy may help determine the definitive therapy for nonmetastatic prostate cancer.

Indexed as

Prostate cancer; Radiotherapy; Lower urinary tract symptoms; Medications

Identifiers

PMID39176291
PMCPMC11337989

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.