Evidence map›Paper›PMID 39176054›Full record

Article... IEEE International Conference on Computer Vision workshops. IEEE International Conference on Computer Vision2023

Robust AMD Stage Grading with Exclusively OCTA Modality Leveraging 3D Volume.

Haochen Zhang, Anna Heinke, Carlo Miguel B Galang, Daniel N Deussen, Bo Wen, Dirk-Uwe G Bartsch, William R Freeman, Truong Q Nguyen, Cheolhong An

Abstract read
In one paragraph

Article in ... IEEE International Conference on Computer Vision workshops. IEEE International Conference on Computer Vision, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. OCTA-based AMD Stage Grading Enhancement via Class-Conditioned Style Transfer.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Haochen ZhangElectrical and Computer Engineering Department, UC San Diego.
Anna HeinkeJacobs Retina Center, Shiley Eye Institute, UC San Diego.
Carlo Miguel B GalangJacobs Retina Center, Shiley Eye Institute, UC San Diego.
Daniel N DeussenJacobs Retina Center, Shiley Eye Institute, UC San Diego.
Bo WenElectrical and Computer Engineering Department, UC San Diego.
Dirk-Uwe G BartschJacobs Retina Center, Shiley Eye Institute, UC San Diego.
William R FreemanJacobs Retina Center, Shiley Eye Institute, UC San Diego.
Truong Q NguyenElectrical and Computer Engineering Department, UC San Diego.
Cheolhong AnElectrical and Computer Engineering Department, UC San Diego.

Funding

SCH: Multimodal Retina Image Alignment and ApplicationsR01EY033847 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AN, CHEOLHONG, BARTSCH, DIRK-UWE G · 2021 to 2024
$1.2M
NEI NIH HHS R01 EY033847
6 · The paper itself

Abstract

Age-related Macular Degeneration (AMD) is a degenerative eye disease that causes central vision loss. Optical Coherence Tomography Angiography (OCTA) is an emerging imaging modality that aids in the diagnosis of AMD by displaying the pathogenic vessels in the subretinal space. In this paper, we investigate the effectiveness of OCTA from the view of deep classifiers. To the best of our knowledge, this is the first study that solely uses OCTA for AMD stage grading. By developing a 2D classifier based on OCTA projections, we identify that segmentation errors in retinal layers significantly affect the accuracy of classification. To address this issue, we propose analyzing 3D OCTA volumes directly using a 2D convolutional neural network trained with additional projection supervision. Our experimental results show that we achieve over 80% accuracy on a four-stage grading task on both error-free and error-prone test sets, which is significantly higher than 60%, the accuracy of human experts. This demonstrates that OCTA provides sufficient information for AMD stage grading and the proposed 3D volume analyzer is more robust when dealing with OCTA data with segmentation errors.

Identifiers

PMID39176054
PMCPMC11340655

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.