Evidence map›Paper›PMID 39175781›Full record

ArticleiScience2024

The role of brown adipose tissue in branched-chain amino acid clearance in people.

Yasser G Abdelhafez, Guobao Wang, Siqi Li, Vanessa Pellegrinelli, Abhijit J Chaudhari, Anthony Ramirez, Fatma Sen, Antonio Vidal-Puig, Labros S Sidossis, Samuel Klein and 2 more

Abstract read
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yasser G AbdelhafezDepartment of Radiology, University of California Davis, Sacramento, CA 95817, USA.
Guobao WangDepartment of Radiology, University of California Davis, Sacramento, CA 95817, USA.
Siqi LiDepartment of Radiology, University of California Davis, Sacramento, CA 95817, USA.
Vanessa PellegrinelliInstitute of Metabolic Science-Metabolic Research Laboratories, Medical Research Council Metabolic Diseases Unit, University of Cambridge, Cambridge CB2 0QQ, UK.
Abhijit J ChaudhariDepartment of Radiology, University of California Davis, Sacramento, CA 95817, USA.
Anthony RamirezDepartment of Nutrition, University of California Davis, Davis, CA 95616, USA.
Fatma SenDepartment of Radiology, University of California Davis, Sacramento, CA 95817, USA.
Antonio Vidal-PuigInstitute of Metabolic Science-Metabolic Research Laboratories, Medical Research Council Metabolic Diseases Unit, University of Cambridge, Cambridge CB2 0QQ, UK.
Labros S SidossisDepartment of Kinesiology and Health, Rutgers University, New Brunswick, NJ 08901, USA.
Samuel KleinCenter for Human Nutrition, Washington University School of Medicine, Saint Louis, MO 63110, USA.
Ramsey D BadawiDepartment of Radiology, University of California Davis, Sacramento, CA 95817, USA.
Maria ChondronikolaDepartment of Radiology, University of California Davis, Sacramento, CA 95817, USA.

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI KC KENT LLOYD · 2002 to 2026
$84.9M
Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 1999 to 2026
$30.2M
WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Clay F. Semenkovich · 2013 to 2026
$27.1M
EXPLORER: Changing the Molecular Imaging Paradigm with Total Body PETR01CA206187 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BADAWI, RAMSEY D., CHERRY, SIMON R · 2015 to 2019
$15.5M
Total-body PET for assessing myofascial painR61AT012187 · NCCIH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHAUDHARI, ABHIJIT J, NARDO, LORENZO · 2022 to 2022
$2.1M
Total-Body PET/CT for assessing Rheumatoid Arthritis Disease Activity and Treatment ResponseR01AR076088 · NIAMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHAUDHARI, ABHIJIT J · 2019 to 2021
$617k
NCATS NIH HHS UL1 TR002345NCCIH NIH HHS R61 AT012187NCI NIH HHS P30 CA093373NCI NIH HHS R01 CA206187NIAMS NIH HHS R01 AR076088NIDDK NIH HHS P30 DK020579NIDDK NIH HHS P30 DK056341Wellcome Trust
6 · The paper itself

Abstract

Brown adipose tissue (BAT) in rodents appears to be an important tissue for the clearance of plasma branched-chain amino acids (BCAAs) contributing to improved metabolic health. However, the role of human BAT in plasma BCAA clearance is poorly understood. Here, we evaluate patients with prostate cancer who underwent positron emission tomography-computed tomography imaging after an injection of

Indexed as

CancerHuman geneticsHuman metabolism

Identifiers

PMID39175781
PMCPMC11340589

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.