Evidence map›Paper›PMID 39175714›Full record

ArticleHepatobiliary surgery and nutrition2024

The application of real-time indocyanine green fluorescence cholangiography in laparoscopic living donor left lateral sectionectomy.

Lu Lu, Wen-Wei Zhu, Cong-Huan Shen, Yi-Feng Tao, Zheng-Xin Wang, Jin-Hong Chen, Lun-Xiu Qin

Abstract read
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Article in Hepatobiliary surgery and nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

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0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Lu Lu *Hepatobiliary Surgery Center, Department of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0002-8245-7252
Wen-Wei Zhu *Hepatobiliary Surgery Center, Department of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Cong-Huan Shen *Liver Transplantation Center, Department of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Yi-Feng TaoLiver Transplantation Center, Department of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Zheng-Xin WangLiver Transplantation Center, Department of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Jin-Hong ChenHepatobiliary Surgery Center, Department of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Lun-Xiu QinHepatobiliary Surgery Center, Department of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0003-4805-8239

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The judgment of the division point of the bile duct has always been one of the difficulties of laparoscopic left lateral sectionectomy (LLLS). The purpose of this study was to assess the effects of indocyanine green (ICG) fluorescence cholangiography during LLLS on the occurrence of biliary complications in both donors and recipients. The optimal dose and injection time of ICG were also investigated. Methods: This is a retrospective cohort study. From October 2016 to December 2022, the clinical data of 103 donors who underwent LLLS and relevant recipients were retrospectively analyzed. According to whether ICG fluorescence cholangiography was used, they were divided into a non-ICG group (n=46) and an ICG group (n=57). Biliary complications were observed and the optimal dose and injection time of ICG were explored. Results: Three donors in the non-ICG group suffered from bile leakage. Four grafts had multiple bile duct openings and biliary complications were observed in the relevant recipients who received these grafts in the non-ICG group. Two recipients had bile leakage, and the other two had biliary stenosis. There was no biliary complications both in donors and recipients in the ICG group. The fluorescence intensity of the liver was 108.1±17.6 at a dose of 0.004 mg/kg 90 minutes after injection, significantly weaker than that at 0.05 mg/kg 30 minutes (200.3±17.6, P=0.001) and 90 minutes after injection (140.2±15.4, P=0.001). The fluorescence intensity contrast value at a dose of 0.004 mg/kg was stronger than that at 0.05 mg/kg, both measured 90 minutes after injection (0.098±0.032 Conclusions: ICG fluorescence cholangiography is safe and feasible in LLLS. It reduces biliary complications in both donors and recipients. The optimal ICG dose was 0.004 mg/kg, and 90 minutes after injection was the best observation time. ICG fluorescence cholangiography is recommended for routine use in LLLS.

Indexed as

Laparoscopic living donor hepatectomy (LLDH)living donor liver transplantation (LDLT)real-time indocyanine green fluorescence cholangiography (real-time ICG fluorescence cholangiography)

Identifiers

PMID39175714
PMCPMC11336537

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.