Evidence map›Paper›PMID 39175509›Full record

ArticleLeukemia research reports2024

Avatrombopag for severe refractory thrombocytopenia in a pediatric patient with ALL following allogeneic hematopoietic stem cell transplantation: A case report.

Emilie J Lynch, Autumn Citta, Constance Alford, John A Ligon, Mansi Dalal, Paul Castillo, Biljana Horn, Natalie Dotson, Giselle Moore-Higgs, Jordan Milner

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia research reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Emilie J LynchDivision of Pediatric Hematology, Oncology, Stem Cell Transplantation, University of Florida, Shands Children's Hospital, Gainesville, FL, USA.
Autumn CittaDivision of Pediatric Hematology, Oncology, Stem Cell Transplantation, University of Florida, Shands Children's Hospital, Gainesville, FL, USA.
Constance AlfordDivision of Pediatric Hematology, Oncology, Stem Cell Transplantation, University of Florida, Shands Children's Hospital, Gainesville, FL, USA.
John A LigonDivision of Pediatric Hematology, Oncology, Stem Cell Transplantation, University of Florida, Shands Children's Hospital, Gainesville, FL, USA.
Mansi DalalDivision of Pediatric Hematology, Oncology, Stem Cell Transplantation, University of Florida, Shands Children's Hospital, Gainesville, FL, USA.
Paul CastilloDivision of Pediatric Hematology, Oncology, Stem Cell Transplantation, University of Florida, Shands Children's Hospital, Gainesville, FL, USA.
Biljana HornDivision of Pediatric Hematology, Oncology, Stem Cell Transplantation, University of Florida, Shands Children's Hospital, Gainesville, FL, USA.
Natalie DotsonDivision of Pediatric Hematology, Oncology, Stem Cell Transplantation, University of Florida, Shands Children's Hospital, Gainesville, FL, USA.
Giselle Moore-HiggsDivision of Pediatric Hematology, Oncology, Stem Cell Transplantation, University of Florida, Shands Children's Hospital, Gainesville, FL, USA.
Jordan MilnerDivision of Pediatric Hematology, Oncology, Stem Cell Transplantation, University of Florida, Shands Children's Hospital, Gainesville, FL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients who receive allogeneic hematopoietic stem cell transplantation (alloHSCT) are at risk for developing persistent thrombocytopenia. Here, we describe treatment with avatrombopag, a thrombopoietin receptor agonist, in a pediatric patient with chronic, severe, transfusion-dependent thrombocytopenia (<10 × 10

Indexed as

Acute lymphoblastic leukemiaAllogeneic stem cell transplantationAvatrombopagSevere immune thrombocytopeniaThrombopoietin receptor agonist

Identifiers

PMID39175509
PMCPMC11340611

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.