Evidence map›Paper›PMID 39175340›Full record

ArticleKorean circulation journal2024

Trends and Outcomes of Acute Myocardial Infarction During the Early COVID-19 Pandemic in the United States: A National Inpatient Sample Study.

Harshith Thyagaturu, Harigopal Sandhyavenu, Anoop Titus, Nicholas Roma, Karthik Gonuguntla, Neel Navinkumar Patel, Anas Hashem, Jinnette Dawn Abbott, Sudarshan Balla, Deepak L Bhatt

Abstract read
In one paragraph

Article in Korean circulation journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Harshith ThyagaturuDepartment of Cardiology, West Virginia University, Morgantown, WV, USA. harshihbk@gmail.com.ORCID https://orcid.org/0000-0002-0457-5851
Harigopal SandhyavenuDepartment of Internal Medicine, Weiss Memorial Hospital, Chicago, IL, USA.ORCID https://orcid.org/0000-0002-2567-6651
Anoop TitusDepartment of Internal Medicine, Saint Vincent Hospital, Worcester, MA, USA.ORCID https://orcid.org/0000-0002-2102-9529
Nicholas RomaDepartment of Internal Medicine, St. Luke's University Hospital Network, Bethlehem, PA, USA.ORCID https://orcid.org/0000-0002-7321-0100
Karthik GonuguntlaDepartment of Cardiology, West Virginia University, Morgantown, WV, USA.ORCID https://orcid.org/0000-0002-5607-7993
Neel Navinkumar PatelDepartment of Internal Medicine, New York Medical College/Landmark Medical Center, Woonsocket, RI, USA.ORCID https://orcid.org/0000-0003-0738-998X
Anas HashemDepartment of Internal Medicine, Rochester General Hospital, Rochester, NY, USA.ORCID https://orcid.org/0000-0002-2008-7110
Jinnette Dawn AbbottDepartment of Medicine, Division of Cardiology, Alpert Medical School of Brown University, Providence, RI, USA.ORCID https://orcid.org/0000-0002-2560-0155
Sudarshan BallaDepartment of Cardiology, West Virginia University, Morgantown, WV, USA.ORCID https://orcid.org/0000-0002-7872-3757
Deepak L BhattMount Sinai Heart, Icahn School of Medicine at Mount Sinai Health System, New York, NY, USA.ORCID https://orcid.org/0000-0002-1278-6245

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI JUDITH FEINBERG · 2012 to 2026
$81.0M
NIGMS NIH HHS 2U54GM104942-07NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

BACKGROUND AND

objectivesThere are limited national data on the trends and outcomes of patients hospitalized with acute myocardial infarction (AMI) during the coronavirus disease 2019 (COVID-19) pandemic. We aimed to evaluate the impact of early COVID-19 pandemic on the trends and outcomes of AMI using the National Inpatient Sample (NIS) database.

methodsThe NIS database was queried from January 2019 to December 2020 to identify adult (age ≥18 years) AMI hospitalizations and were categorized into ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI) based on International Classification of Diseases, Tenth Revision, Clinical Modification codes. In addition, the in-hospital mortality, revascularization, and resource utilization of AMI hospitalizations early in the COVID-19 pandemic (2020) were compared to those in the pre-pandemic period (2019) using multivariate logistic and linear regression analysis.

resultsAmongst 1,709,480 AMI hospitalizations, 209,450 STEMI and 677,355 NSTEMI occurred in 2019 while 196,230 STEMI and 626,445 NSTEMI hospitalizations occurred in 2020. Compared with those in 2019, the AMI hospitalizations in 2020 had higher odds of in-hospital mortality (adjusted odds ratio [aOR], 1.27; 95% confidence interval [CI], [1.23-1.32]; p<0.01) and lower odds of percutaneous coronary intervention (aOR, 0.95 [0.92-0.99]; p=0.02), and coronary artery bypass graft (aOR, 0.90 [0.85-0.97]; p<0.01).

conclusionsWe found a significant decline in AMI hospitalizations and use of revascularization, with higher in-hospital mortality, during the early COVID-19 pandemic period (2020) compared with the pre-pandemic period (2019). Further research into the factors associated with increased mortality could help with preparedness in future pandemics.

Indexed as

Acute coronary syndromesCoronavirusCOVID-19Myocardial infarctionPercutaneous coronary intervention

Identifiers

PMID39175340
PMCPMC11569940

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.