ReviewJournal of gastroenterology and hepatology2024
Closure methods for large defects after gastrointestinal endoscopic submucosal dissection.
Review in Journal of gastroenterology and hepatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed.
- Through-the-scope twin clip for closure of gastric endoscopic full-thickness resection defects: a retrospective comparative study.Annals of medicine · 2026Article
- Dual-hook clip closure for high-tension gastric defects.Endoscopy · 2026Article
- Postlobectomy bronchoesophageal fistula treated with endoscopic helical tacking system and anchor-pronged clip.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2026Article
- Feasibility of Zeosuture M for gastric endoscopic submucosal dissection defect closure during anticoagulation: a preclinical porcine study from Japan.Clinical endoscopy · 2026Article
- Muscle-clipping suturing for closure of a gastric defect after endoscopic submucosal dissection for a type 3 neuroendocrine neoplasm.Endoscopy · 2026Article
- Review
- A >30-cm circumferential rectal laterally spreading tumor treated with multitunnel endoscopic submucosal dissection and suturing.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2026Article
- Hemostasis using traction clip closure and self-assembling peptide gel for gastric endoscopic submucosal dissection ulcer.Endoscopy · 2026Article
- Through-the-scope twin clip for endoscopic closure of gastrointestinal defects: efficacy, safety, and factors influencing closure speed.Surgical endoscopy · 2026Observational
- Endoscopic submucosal dissection: Challenges, innovations, and the road ahead.World journal of gastrointestinal endoscopy · 2026Review
- Targeted In-Defect Clipping After Colonic Endoscopic Resection: A Prospective Feasibility Study.Endoscopy international open · 2026Article
- Endoscopic management for gastrointestinal leaks, perforations, and fistulae: Technical tips and outcomes.World journal of gastrointestinal endoscopy · 2025Review
- Endoscopic resection for small rectal gastrointestinal stromal tumors: a pilot study.BMC gastroenterology · 2025Article
- Article
- Article
- Article
- Endoscopic closure of a congenital tracheo-esophageal fistula using a through-the-scope suturing device in a young boy.Endoscopy · 2025Article
- An innovative approach to close large mucosal defects post-endoscopic submucosal sissection: threads combined with endoclips.Endoscopy · 2025Article
- Endoscopic Closure Techniques for Perforations, Leaks, and Fistulae: Review Article.GE Portuguese journal of gastroenterology · 2025Review
- Anchoring of esophageal stents with through-the-scope suturing devices: Preclinical proof of concept and first clinical cases.Endoscopy international open · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Nowadays, endoscopic submucosal dissection (ESD) is commonly performed for the removal of large gastrointestinal lesions. Endoscopic mucosal defect closure after ESD is vital to avoid adverse events. In recent years, many innovative instruments have emerged and proved to be beneficial. In this paper, we conducted a thorough literature review and summarized the closure methods for large-size post-ESD mucosal defects over decades. We separated these methods into five categories based on the operational principle: "side closure" method, "ring closure" method, "layered closure" method, "hand suturing closure" method, and "specially designed device closure" method. Side closure with clips assisted by instruments such as threads or loops is applicable for each segment of the gastrointestinal tract to prevent postoperative bleeding. If the defect tension is too large to close with the traditional side closure methods, zigzag closure and ring closure could be applied to gather the bilateral defect edges together and achieve continuous closure. In the stomach and rectum with a high risk of submucosal dead space between the submucosa and muscular layers, side closure methods with muscle layer grasping clip or layered closure methods could enable the involvement of the deep submucosa and muscle layers. The ring closure method and specially designed devices including over-the-scope clip, Overstitch, and X-tack could resolve perforation effectively. Individual closure method requires endoscope reinsertion or sophisticated operation, which may be limited by the deep location and the narrow lumen, respectively. Although specially designed devices are expected to offer promising prospectives, the cost-effectiveness remains to be a problem.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.