Evidence map›Paper›PMID 39175206›Full record

SynthesisJournal of clinical hypertension (Greenwich, Conn.)2024

Predictive significance of cardio ankle vascular index for the assessment of cardiovascular risk in hypertensive patients: A systematic review.

Chiranjeevee R Saravanan, Shubhayu R Chowdhury, Pugazhendi Inban, Sai Harini Chandrasekaran, Himani H Pattani, Krupanagram Santoshi, Hyma Bamba, Gurmehar Singh, Priyadarshi Prajjwal, Raunak Ranjan and 2 more

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of clinical hypertension (Greenwich, Conn.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chiranjeevee R SaravananInternal Medicine, Madras Medical College, Chennai, India.
Shubhayu R ChowdhuryCardiology, Lincoln County Hospital, Lincoln, UK.
Pugazhendi InbanInternal Medicine, St. Mary's General Hospital and Saint Clare's Health, New York, New York, USA.
Sai Harini ChandrasekaranInternal Medicine, Vijaya Hospitals, Chennai, India.
Himani H PattaniInternal Medicine, Gujarat University, Ahmedabad, India.
Krupanagram SantoshiInternal Medicine, MNR Medical College, Sangareddy, India.
Hyma BambaInternal Medicine, Government Medical College and Hospital, Chandigarh, India.
Gurmehar SinghInternal Medicine, Government Medical College and Hospital, Chandigarh, India.
Priyadarshi PrajjwalInternal Medicine, Bharati Vidyapeeth Medical College Pune, Pune, India.
Raunak RanjanSCGMC Nanded, Nanded, India.
Mohammed Dheyaa Marsool MarsoolInternal Medicine, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq.ORCID 0000-0002-3481-4534
Omniat AmirInternal Medicine, Al-Manhal Academy, Khartoum, Sudan.ORCID 0000-0002-5021-263X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardio-ankle vascular index (CAVI) is an innovative indicator of large-artery stiffness, which is evaluated by the pulse wave velocity (PWV) measurement. Mortality and morbidity due to cardiovascular diseases among the general public with high-risk conditions such as hypertension are usually associated with arterial stiffness. CAVI modelizes the hazard of future cardiovascular events with standard risk factors. Additionally, the "European Society of Hypertension and Cardiology" included the aortic PWV assessment in managing hypertension in their updated guidelines in 2007. We conducted this systematic review to collect, summarize, and evaluate the evidence from relevant reported studies. A literature search of four databases was conducted comprehensively until February 2024. Cardiovascular events are the primary outcome of interest in this study, cardiovascular events that have been defined as major adverse cardiac events include "heart failure", "stroke", "myocardial infarction", "cardiovascular deaths", "stable angina pectoris", "coronary revascularization", and "unstable angina pectoris". We included five studies with a 11 698 sample size in this systematic review. All five prospective studies investigated composite cardiovascular events as an outcome. Three of them revealed a statistically significant prediction ability of CAVI to assess Cardiovascular disease (CVD) risk. Further analysis is required. Current evidence is insufficient to confirm the predictive power of CAVI in the assessment of cardiovascular risk in hypertensive patients. CAVI is modestly associated with incidents of CVD risk. It is necessary to conduct further studies to assess CAVI concerning CVD predictor measures in the masses and nations other than Asia.

Indexed as

Cardio Ankle Vascular IndexCardiovascular DiseasesHypertensionPulse Wave AnalysisVascular StiffnessHeart Disease Risk FactorsHumansPredictive Value of TestsRisk AssessmentRisk Factorsarterial stiffnesscardio ankle vascular indexcardiovascular diseasesCAVIhypertensionpredictive significance

Identifiers

PMID39175206
PMCPMC11488310

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.