Evidence map›Paper›PMID 39175032›Full record

ArticleJournal of orthopaedic surgery and research2024

Stochastic lattice-based porous implant design for improving the stress transfer in unicompartmental knee arthroplasty.

Tao Deng, Shan Gong, Yiwei Cheng, Junqing Wang, Hui Zhang, Kang Li, Yong Nie, Bin Shen

Abstract read
In one paragraph

Article in Journal of orthopaedic surgery and research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Tao Deng *Department of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, 610041, China.
Shan Gong *Sichuan University-Pittsburgh Institute, Sichuan University, Chengdu, 610207, China.
Yiwei ChengSichuan University-Pittsburgh Institute, Sichuan University, Chengdu, 610207, China.
Junqing WangDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, 610041, China.
Hui ZhangDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, 610041, China.
Kang LiWest China Biomedical Big Data Center, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, P.R. China. likang@wchscu.cn.
Yong NieDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, 610041, China. nieyong1983@wchscu.cn.
Bin ShenDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, 610041, China.

Funding

0-1 Innovation Project of Sichuan University 2022SCUH00151·3·5 project for disciplines of excellence-Clinical Research Fund, West China Hospital, Sichuan University 2023HXFH0241•3•5 project for disciplines of excellence, West China Hospital, Sichuan University ZYAI24038Medico-Engineering Cooperation Funds from University of Electronic Science and Technology by the Fundamental Research Funds for the Central Universities ZYGX2022YGRH007National Key Research and Development Program 2023YFB4606700the 1•3•5 project for disciplines of excellence, West China Hospital, Sichuan University ZYYC21004the National Key Research and Development Program of China 2020YFB1711500
6 · The paper itself

Abstract

backgroundUnicompartmental knee arthroplasty (UKA) has been proved to be a successful treatment for osteoarthritis patients. However, the stress shielding caused by mismatch in mechanical properties between human bones and artificial implants remains as a challenging issue. This study aimed to properly design a bionic porous tibial implant and evaluate its biomechanical effect in reconstructing stress transfer pathway after UKA surgery.

methodsVoronoi structures with different strut sizes and porosities were designed and manufactured with Ti6Al4V through additive manufacturing and subjected to quasi-static compression tests. The Gibson-Ashby model was used to relate mechanical properties with design parameters. Subsequently, finite element models were developed for porous UKA, conventional UKA, and native knee to evaluate the biomechanical effect of tibial implant with designed structures during the stance phase.

resultsThe internal stress distribution on the tibia plateau in the medial compartment of the porous UKA knee was found to closely resemble that of the native knee. Furthermore, the mean stress values in the medial regions of the tibial plateau of the porous UKA knee were at least 44.7% higher than that of the conventional UKA knee for all subjects during the most loading conditions. The strain shielding reduction effect of the porous UKA knee model was significant under the implant and near the load contact sites. For subject 1 to 3, the average percentages of nodes in bone preserving and building region (strain values range from 400 to 3000 μm/m) of the porous UKA knee model, ranging from 68.7 to 80.5%, were higher than that of the conventional UKA knee model, ranging from 61.6 to 68.6%.

conclusionsThe comparison results indicated that the tibial implant with designed Voronoi structure offered better biomechanical functionality on the tibial plateau after UKA. Additionally, the model and associated analysis provide a well-defined design process and dependable selection criteria for design parameters of UKA implants with Voronoi structures.

Indexed as

Arthroplasty, Replacement, KneeFinite Element AnalysisKnee ProsthesisProsthesis DesignStress, MechanicalAlloysBiomechanical PhenomenaHumansPorosityTibiaTitaniumAlloysTitaniumtitanium alloy (TiAl6V4)Additive manufacturingBone stress transfer pathwayFinite element analysisPorous implantsUnicompartmental knee arthroplasty

Identifiers

PMID39175032
PMCPMC11340161

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.