Evidence map›Paper›PMID 39174887›Full record

ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2024

Virulence gene distribution and molecular epidemiological characteristics of carbapenem-resistant

Yaxuan Huang, Yihan Cai, Wanxia He, Liyan Zhang, Yue Zhao

Abstract read
In one paragraph

Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Clinical Epidemiological Analysis of the Genotypic Spectrum and Mortality Risk in Carbapenem-ResistantThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yaxuan HuangDepartment of Clinical Laboratory, Guangdong Provincial People's Hospital/Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou 510080, China. huangyaxuan2001@126.com.
Yihan CaiDepartment of Clinical Laboratory, Xiaolan People's Hospital of Zhongshan/Fifth People's Hospital of Zhongshan, Zhongshan Guangdong 528415, China.
Wanxia HeYunkang School of Medicine and Health, Guangzhou Nanfang College, Guangzhou 510970, China.
Liyan ZhangDepartment of Clinical Laboratory, Guangdong Provincial People's Hospital/Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou 510080, China.
Yue ZhaoDepartment of Clinical Laboratory, Guangdong Provincial People's Hospital/Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou 510080, China. zhaoyue@gdph.org.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe drug-resistant genes carried by carbapenem-resistant

methodsA total of 40 non-duplicate strains of CRKP isolated from the ICU of Guangdong Provincial People's Hospital between January 2021 and December 2022 were collected and analyzed. Whole-genome sequencing was used to analyze the distribution of resistance genes, virulence genes, and capsular serotypes of the strains. The sequences of 7 housekeeping genes of CRKP genome were uploaded to the

resultsThe age of the 40 ICU CRKP-infected patients was (69.03±17.82) years old, with various underlying diseases, and there were 20 patients with improved clinical outcome and 20 patients with death. The isolated strains primarily originated from mid-stream urine and bronchoalveolar lavage fluid. Whole-genome sequencing results revealed that the strains predominantly carried

conclusionsThe main type of ICU CRKP is ST11-KL64, carrying various virulence genes, primarily those related to iron absorption. Furthermore,

Indexed as

CarbapenemsIntensive Care UnitsKlebsiella InfectionsKlebsiella pneumoniaeWhole Genome SequencingAgedAnti-Bacterial Agentsbeta-LactamasesCarbapenem-Resistant EnterobacteriaceaeFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedMolecular EpidemiologyMultilocus Sequence TypingAnti-Bacterial Agentsbeta-LactamasesCarbapenemsVirulence Factorscapsular serotypescarbapenem-resistant Klebsiella pneumoniaeintensive care unitmolecular epidemiologymultilocus sequence typingvirulence geneswhole-genome sequencing

Identifiers

PMID39174887
PMCPMC11341222

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.