Evidence map›Paper›PMID 39174872›Full record

ArticlePhysiological reports2024

Effects of a 217-km mountain ultramarathon on the gut microbiota of an obese runner: A case report.

Giulio Kai Saragiotto, Luiz Felipe Valter de Oliveira, Nayara Kastem Scharlack, Milena Merizzi de Oliveira, Fernanda Campos Freire, Fernando Moreira Simabuco, Katia Sivieri, Adilson Sartoratto, Taisa Belli, Adriane Elisabete Costa Antunes

Abstract readCase Reports
In one paragraph

Article in Physiological reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giulio Kai SaragiottoFaculdade de Ciências Aplicadas, Universidade Estadual de Campinas (FCA/UNICAMP), Limeira, São Paulo, Brazil.ORCID 0000-0002-8240-4644
Luiz Felipe Valter de OliveiraDepartment of Biotechnologies, BiomeHub, Florianópolis, Santa Catarina, Brazil.ORCID 0000-0003-4535-0621
Nayara Kastem ScharlackFaculdade de Ciências Aplicadas, Universidade Estadual de Campinas (FCA/UNICAMP), Limeira, São Paulo, Brazil.ORCID 0000-0002-4072-6135
Milena Merizzi de OliveiraFaculdade de Ciências Aplicadas, Universidade Estadual de Campinas (FCA/UNICAMP), Limeira, São Paulo, Brazil.ORCID 0009-0006-9795-0863
Fernanda Campos FreireSchool of Pharmaceutical Sciences, State University of São Paulo "Júlio de Mesquita Filho" (UNESP), Araraquara, São Paulo, Brazil.ORCID 0000-0003-3475-4196
Fernando Moreira SimabucoFaculdade de Ciências Aplicadas, Universidade Estadual de Campinas (FCA/UNICAMP), Limeira, São Paulo, Brazil.ORCID 0000-0002-1672-9686
Katia SivieriSchool of Pharmaceutical Sciences, State University of São Paulo "Júlio de Mesquita Filho" (UNESP), Araraquara, São Paulo, Brazil.ORCID 0000-0001-8632-1478
Adilson SartorattoCentro Pluridisciplinar de Pesquisas Químicas, Biológicas e Agrícolas, Universidade Estadual de Campinas (CPQBA/UNICAMP), Paulínia, São Paulo, Brazil.ORCID 0000-0002-1763-3715
Taisa BelliFaculdade de Ciências Aplicadas, Universidade Estadual de Campinas (FCA/UNICAMP), Limeira, São Paulo, Brazil.ORCID 0000-0002-6755-1099
Adriane Elisabete Costa AntunesFaculdade de Ciências Aplicadas, Universidade Estadual de Campinas (FCA/UNICAMP), Limeira, São Paulo, Brazil.ORCID 0000-0002-1548-1367

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) 303772/2022-0Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) 001UNICAMP | Fundo de Apoio ao Ensino, à Pesquisa e Extensão, Universidade Estadual de Campinas (FAEPEX, UNICAMP) 2160/23
6 · The paper itself

Abstract

Obesity is characterized by specific changes in the composition of the gut microbiota (GM). Exercise can contribute to the modulation of GM. This is the first case study to analyze the composition and metabolism of the GM of an obese runner in a single-stage mountain ultramarathon (MUM) with a mileage of 217 km. Fecal samples were collected 7 days before the race (T0), 15 min after the end of the race (T1), and 7 days after the end of the race (T2). GM composition was analyzed by real-time PCR and shotgun sequencing. We observed a decrease in Bacillota/Bacteroidota ratio and α-diversity after the race. After the 217-km MUM, we observed a decrease in symbiont microorganisms and a notable increase in harmful bacteria. In conclusion, we found that the 217-km MUM may have contributed to the intestinal dysbiosis of the obese runner.

Indexed as

Gastrointestinal MicrobiomeObesityAdultDysbiosisFecesHumansMaleMarathon RunningMiddle AgedRunninggut microbiotaobese runnerpathobionts bacteriaultramarathon

Identifiers

PMID39174872
PMCPMC11341271

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.