Evidence map›Paper›PMID 39174654›Full record

ArticleEuropean radiology2025

Complications of ultrasound-guided thermal ablation of thyroid nodules and associated risk factors: an experience from 9667 cases.

Xi Liang, Bo Jiang, Yongjiao Ji, Yanna Xu, Yanting Lv, Si Qin, Lanlan Huo, Huimiao Zhang, Hongrui Liu, Tongming Shi and 1 more

Abstract read
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Article in European radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xi LiangDepartment of Ultrasound, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Bo JiangDepartment of Ultrasound, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Yongjiao JiDepartment of Ultrasound, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Yanna XuDepartment of Ultrasound, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Yanting LvDepartment of Ultrasound, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Si QinDepartment of Ultrasound, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Lanlan HuoDepartment of Ultrasound, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Huimiao ZhangDepartment of Ultrasound, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Hongrui LiuDepartment of Ultrasound, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Tongming ShiDepartment of Ultrasound, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Yukun LuoDepartment of Ultrasound, The First Medical Center, Chinese PLA General Hospital, Beijing, China. lyk301@163.com.ORCID http://orcid.org/0000-0002-5944-8198

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the safety of ultrasound-guided thermal ablation (UGTA) for thyroid nodules (TNs) by analysing complications and related risks. MATERIALS AND

methodsThis retrospective, single-centre study reviewed patients who underwent UGTA (microwave or radiofrequency ablation) between January 2018 and March 2023. The incidence of complications was recorded and assessed during and immediately after ablation,1-3 h later, and at 1 month, 3 months, and 6 months. Univariate and multivariate analyses were performed to identify risk factors for hoarseness and haemorrhagic complications.

resultsWe reviewed 9667 cases in this study. Overall, 4494 (46.49%) cases underwent microwave ablation, while 5173 (53.51%) cases underwent radiofrequency ablation. The overall complication rate was 4.43%. The incidence of major complications was 1.94% (haemorrhage, 1.32%; hoarseness, 0.54%; and symptomatic aseptic necrosis, 0.08%). The incidence of minor complications was 2.45%. A large nodule volume, radiofrequency ablation, hyper-enhancing nodules, benign nodules, higher preoperative blood pressure, hyperthyroidism, and higher ablation power were independent risk factors for haemorrhage. Dorsal nodules and a higher ablation power were independent risk factors for hoarseness. All complications were resolved.

conclusionThis study suggests that UGTA is a safe treatment for TNs. Several risk factors for haemorrhage and hoarseness should be considered before performing UGTA. Different ablation modalities should be considered for patients with different conditions. CLINICAL RELEVANCE STATEMENT: Thermal ablation may be a safe treatment for eligible patients with TNs. KEY POINTS: We analysed the complications and risk factors associated with UGTA in 9667 cases. The complication rate was 4.43%; 1.94% were major complications. Risk factors of haemorrhage and hoarseness should be considered. UGTA was a safe method for the treatment of TNs.

Indexed as

Postoperative ComplicationsRadiofrequency AblationThyroid NoduleUltrasonography, InterventionalAdultAgedFemaleHumansMaleMicrowavesMiddle AgedRetrospective StudiesRisk FactorsPostoperative complicationsThermal ablation, Thyroid nodule

Identifiers

PMID39174654

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.