Evidence map›Paper›PMID 39174560›Full record

ReviewNature communications2024

Sleep-like cortical dynamics during wakefulness and their network effects following brain injury.

Marcello Massimini, Maurizio Corbetta, Maria V Sanchez-Vives, Thomas Andrillon, Gustavo Deco, Mario Rosanova, Simone Sarasso

Abstract readReview
In one paragraph

Review in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Review
  2. Covert brain complexity in the intensive care unit.Cortex; a journal devoted to the study of the nervous system and behavior · 2026
    Article
  3. Article
  4. Article
  5. Spatially structured heterogeneity shapes large-scale cortical dynamics in a model of the human cortex.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Clinical utility and prospective of TMS-EEG: Updated review from an international expert group.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2026
    Review
  10. Review
  11. Clinical significance of ADHD traits in central disorders of hypersomnolence.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Article
  12. A complex network perspective on brain disease.Biological reviews of the Cambridge Philosophical Society · 2026
    Review
  13. Brain-wide properties of slow waves across vigilance states.Sleep advances : a journal of the Sleep Research Society · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Brain Oscillatory Modes as a Proxy of Stroke Recovery.Neurorehabilitation and neural repair · 2025
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marcello MassiminiDepartment of Biomedical and Clinical Sciences, University of Milan, Milan, Italy. marcello.massimini@unimi.it.ORCID 0000-0003-2271-957X
Maurizio CorbettaDepartment of Neuroscience and Padova Neuroscience Center (PNC), University of Padova, Padova, Italy.ORCID 0000-0001-8295-3304
Maria V Sanchez-VivesInstitut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.ORCID 0000-0002-8437-9083
Thomas AndrillonSorbonne Université, Institut du Cerveau - Paris Brain Institute - ICM, Mov'it team, Inserm, CNRS, Paris, France.
Gustavo DecoInstitució Catalana de la Recerca i Estudis Avançats (ICREA), Barcelona, Spain.ORCID 0000-0002-8995-7583
Mario RosanovaDepartment of Biomedical and Clinical Sciences, University of Milan, Milan, Italy.ORCID 0000-0001-7486-7617
Simone SarassoDepartment of Biomedical and Clinical Sciences, University of Milan, Milan, Italy.ORCID 0000-0001-9984-4710

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

By connecting old and recent notions, different spatial scales, and research domains, we introduce a novel framework on the consequences of brain injury focusing on a key role of slow waves. We argue that the long-standing finding of EEG slow waves after brain injury reflects the intrusion of sleep-like cortical dynamics during wakefulness; we illustrate how these dynamics are generated and how they can lead to functional network disruption and behavioral impairment. Finally, we outline a scenario whereby post-injury slow waves can be modulated to reawaken parts of the brain that have fallen asleep to optimize rehabilitation strategies and promote recovery.

Indexed as

Brain InjuriesElectroencephalographySleepWakefulnessAnimalsBrainCerebral CortexHumansNerve Net

Identifiers

PMID39174560
PMCPMC11341729

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.