Evidence map›Paper›PMID 39174323›Full record

ArticleTobacco control2025

Changing patterns of cigarette and ENDS transitions in the USA: a multistate transition analysis of adults in the PATH Study in 2017-2019 vs 2019-2021.

Andrew F Brouwer, Jihyoun Jeon, Evelyn Jimenez-Mendoza, Stephanie R Land, Theodore R Holford, Abigail S Friedman, Jamie Tam, Ritesh Mistry, David T Levy, Rafael Meza

Abstract read
In one paragraph

Article in Tobacco control, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Continuous associations of the brief Wisconsin Inventory of Smoking Dependence Motives with transitions between cigarette and e-cigarette use.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Andrew F BrouwerEpidemiology, University of Michigan, Ann Arbor, Michigan, USA brouweaf@umich.edu.ORCID 0000-0002-3779-5287
Jihyoun JeonEpidemiology, University of Michigan, Ann Arbor, Michigan, USA.
Evelyn Jimenez-MendozaEpidemiology, University of Michigan, Ann Arbor, Michigan, USA.
Stephanie R LandTobacco Control Research Branch, National Cancer Institute Division of Cancer Control and Population Sciences, Rockville, Maryland, USA.
Theodore R HolfordBiostatistics, Yale University, New Haven, Connecticut, USA.
Abigail S FriedmanHealth Management and Policy, Yale University, New Haven, Connecticut, USA.ORCID 0000-0002-2352-8786
Jamie TamHealth Management and Policy, Yale University, New Haven, Connecticut, USA.ORCID 0000-0001-8353-4259
Ritesh MistryHealth Behavior Health Education, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0003-1514-1466
David T LevyLombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA.ORCID 0000-0001-5280-3612
Rafael MezaIntegrative Oncology, BC Cancer Research Centre, Vancouver, British Columbia, Canada.

Funding

Research Project 3: Modeling the Impact of Tobacco Control Policies on Polytobacco Use and Associated Health DisparitiesU54CA229974 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI David Theodore Levy · 2018 to 2026
$39.2M
Comparative Modeling of Lung Cancer Prevention, Early Detection and Treatment InterventionsU01CA253858 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DE KONING, HARRY J, HOLFORD, THEODORE R · 2020 to 2025
$8.4M
Health and economic impact analysis of a reduced nicotine cigarette policy on vulnerable populationsK01DA056424 · NIDA · YALE UNIVERSITY · PI Jamie Pearl Tam · 2022 to 2026
$829k
NCI NIH HHS U01 CA253858NCI NIH HHS U54 CA229974NIDA NIH HHS K01 DA056424
6 · The paper itself

Abstract

introductionThe use of cigarettes and electronic nicotine delivery system (ENDS) has likely changed since 2019 with the rise of pods and disposables, the lung injuries outbreak, flavour bans, Tobacco 21 and the COVID-19 pandemic.

methodsUsing the Population Assessment of Tobacco and Health Study, we applied a multistate transition model to 28 061 adults in waves 4-5 (2017-2019) and 24 584 adults in waves 5-6 (2019-2021), estimating transition rates for initiation, cessation and switching products for each period overall and by age group.

resultsCigarette initiation among adults who never used either product decreased from 2017-2019 to 2019-2021, but ENDS initiation did not significantly change. The persistence of ENDS-only use remained high (75%-80% after 1 year). Cigarette-only use transitions remained similar (88% remaining, 7% to non-current use and 5% to dual or ENDS-only use). In contrast, dual use to ENDS-only transitions increased from 9.5% (95% CI 7.3% to 11.7%) to 20.0% (95% CI 17.4% to 22.6%) per year, decreasing the persistence of dual use. The dual to cigarette-only use transition remained at about 25%. These changes were qualitatively similar across adult age groups, though adults ages 18-24 years exhibited the highest probability of switching from cigarette-only use to dual use and from dual use to ENDS-only use.

conclusionsThe persistence of ENDS use among adults remained high in 2019-2021, but a larger fraction of dual users transitioned to ENDS-only use compared with 2017-2019. Because the fraction of cigarette-only users switching to dual use remained low, especially among older adults, the public health implications of this change are minimal.

Indexed as

Cigarette SmokingElectronic Nicotine Delivery SystemsTobacco ProductsVapingAdolescentAdultAgedCOVID-19FemaleHumansMaleMiddle AgedSmoking CessationUnited StatesYoung AdultCessationCOVID-19Electronic nicotine delivery devicesSurveillance and monitoring

Identifiers

PMID39174323
PMCPMC12080509

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.