Evidence map›Paper›PMID 39173918›Full record

ArticleThe Journal of infection2024

Frequency of antimicrobial-resistant bloodstream infections in 111 hospitals in Thailand, 2022.

Krittiya Tuamsuwan, Panida Chamawan, Phairam Boonyarit, Voranadda Srisuphan, Preeyarach Klaytong, Chalida Rangsiwutisak, Prapass Wannapinij, Trithep Fongthong, John Stelling, Paul Turner and 1 more

Abstract read
In one paragraph

Article in The Journal of infection, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Krittiya TuamsuwanThe Office of Permanent Secretary, Ministry of Public Health, Nonthaburi, Thailand.
Panida ChamawanThe Office of Permanent Secretary, Ministry of Public Health, Nonthaburi, Thailand.
Phairam BoonyaritThe Office of Permanent Secretary, Ministry of Public Health, Nonthaburi, Thailand.
Voranadda SrisuphanThe Office of Permanent Secretary, Ministry of Public Health, Nonthaburi, Thailand.
Preeyarach KlaytongMahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Chalida RangsiwutisakMahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Prapass WannapinijMahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Trithep FongthongThe Office of Permanent Secretary, Ministry of Public Health, Nonthaburi, Thailand.
John StellingBrigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Paul TurnerMahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Cambodia-Oxford Medical Research Unit, Angkor Hospital for Children, Siem Reap, Cambodia; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Direk LimmathurotsakulMahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. Electronic address: direk@tropmedres.ac.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the frequency of antimicrobial-resistant bloodstream infections (AMR BSI) in Thailand.

methodsWe analyzed data from 2022, generated by 111 public hospitals in health regions 1 to 12, using the AutoMated tool for Antimicrobial resistance Surveillance System (AMASS), and submitted to the Ministry of Public Health, Thailand. Multilevel Poisson regression models were used.

resultsThe most common cause of community-origin AMR BSI was third-generation cephalosporin-resistant Escherichia coli (3GCREC, 65.6%; 5101/7773 patients) and of hospital-origin AMR BSI was carbapenem-resistant Acinetobacter baumannii (CRAB, 51.2%, 4968/9747 patients). The percentage of patients tested for BSI was negatively associated with the frequency of community-origin 3GCREC BSI and hospital-origin CRAB BSI (per 100,000 tested patients). Hospitals in health regions 4 (lower central region) had the highest frequency of community-origin 3GCREC BSI (adjusted incidence rate ratio, 2.06; 95% confidence interval: 1.52-2.97). Health regions were not associated with the frequency of hospital-origin CRAB BSI, and between-hospital variation was high, even adjusting for hospital level and size.

conclusionThe high between-hospital variation of hospital-origin CRAB BSI suggests the importance of hospital-specific factors. Our approach and findings highlight health regions and hospitals where actions against AMR infection, including antimicrobial stewardship and infection control, should be prioritized.

Indexed as

Anti-Bacterial AgentsBacteremiaCross InfectionAcinetobacter baumanniiAdolescentAdultAgedAged, 80 and overChildChild, PreschoolCommunity-Acquired InfectionsDrug Resistance, BacterialFemaleHospitalsHospitals, PublicHumansAnti-Bacterial AgentsAntimicrobial resistantBloodstream infectionFrequencyIncidenceProportionSurveillance

Identifiers

PMID39173918
PMCPMC11409609

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.