Evidence map›Paper›PMID 39173010›Full record

ArticleThe ISME journal2024

Temperature modulates dominance of a superinfecting Arctic virus in its unicellular algal host.

Claudia Meyer, Victoria L N Jackson, Keith Harrison, Ioanna Fouskari, Henk Bolhuis, Yael A Artzy-Randrup, Jef Huisman, Adam Monier, Corina P D Brussaard

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The ISME journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Claudia MeyerDepartment of Marine Microbiology and Biogeochemistry, NIOZ Royal Netherlands Institute for Sea Research, PO Box 59, 1790AB Den Burg, Texel, The Netherlands.
Victoria L N JacksonLiving Systems Institute, University of Exeter, Exeter, Devon EX4 4QD, United Kingdom.
Keith HarrisonLiving Systems Institute, University of Exeter, Exeter, Devon EX4 4QD, United Kingdom.
Ioanna FouskariDepartment of Marine Microbiology and Biogeochemistry, NIOZ Royal Netherlands Institute for Sea Research, PO Box 59, 1790AB Den Burg, Texel, The Netherlands.
Henk BolhuisDepartment of Marine Microbiology and Biogeochemistry, NIOZ Royal Netherlands Institute for Sea Research, PO Box 59, 1790AB Den Burg, Texel, The Netherlands.
Yael A Artzy-RandrupDepartment of Theoretical and Computational Ecology, Institute for Biodiversity and Ecosystem Dynamics (IBED), University of Amsterdam, PO Box 94240, 1090 GE Amsterdam, The Netherlands.
Jef HuismanDepartment of Freshwater and Marine Ecology, Institute for Biodiversity and Ecosystem Dynamics (IBED), University of Amsterdam, PO Box 94240, 1090 GE Amsterdam, The Netherlands.
Adam MonierLiving Systems Institute, University of Exeter, Exeter, Devon EX4 4QD, United Kingdom.
Corina P D BrussaardDepartment of Marine Microbiology and Biogeochemistry, NIOZ Royal Netherlands Institute for Sea Research, PO Box 59, 1790AB Den Burg, Texel, The Netherlands.

Funding

Royal Society University Research Fellowship URF\R1\180537University of Amsterdam and NIOZ Royal Netherlands Institute for Sea ResearchUniversity of Exeter Sequencing ServiceWellcome TrustWellcome Trust 218247/Z/19/Z
6 · The paper itself

Abstract

Complex virus-virus interactions can arise when multiple viruses coinfect the same host, impacting infection outcomes with broader ecological and evolutionary significance for viruses and host. Yet, our knowledge regarding virus competition is still limited, especially for single-celled eukaryotic host-virus systems. Here, we report on mutual interference of two dsDNA viruses, MpoV-45T and MpoV-46T, competing for their Arctic algal host Micromonas polaris. Both viruses affected each other's gene expression and displayed reduced genome replication during coinfection. MpoV-45T was the dominant virus, likely due to interference in the DNA replication of is competitor. Even when its coinfection was delayed, the dominant virus still prevailed while genome production of the other virus was strongly suppressed. This contrasts with typical superinfection exclusion, where the primary infection prevents secondary infection by other viruses. Higher temperature made the suppressed virus a stronger competitor, signifying that global warming is likely to alter virus-virus interactions in Arctic waters.

Indexed as

DNA VirusesArctic RegionsChlorophytaCoinfectionTemperatureVirus ReplicationArctic Oceancoinfectionmarine phytoplanktontranscriptomicsviral genomevirus–virus interactions

Identifiers

PMID39173010
PMCPMC11370638

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.