SynthesisPloS one2024
Association between post-stroke depression and functional outcomes: A systematic review.
Synthesis in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The association between systemic immune-inflammation index and post-stroke depression: a meta-analysis.Frontiers in psychiatry · 2026Pooled it
- Pooled it
- Early emotional interventions for post-stroke functional prognosis: a systematic review and meta-analysis.Frontiers in neurologyPooled it
- Lactylation and N6-Methyladenosine RNA modification in neuropsychiatric sequelae after intracerebral hemorrhage: a hypothesis-generating metabolic-glial-circuit framework.Molecular biology reports · 2026Review
- Validating an aphasia-accessible ecological momentary assessment for daily depressive affect: A preliminary investigation.Journal of affective disorders · 2026Article
- Clinical Outcomes of Phased Rehabilitation Nursing Combined With Mindfulness-Based Stress Reduction in Patients With Acute Cerebral Infarction.Actas espanolas de psiquiatria · 2026Article
- Heterogeneity in symptom burden and supportive care needs among older adults with ischemic stroke: a cross-sectional study.BMC geriatrics · 2026Article
- Analysis of Prognostic Factors Affecting Quality of Life After Ischemic Stroke.Journal of clinical medicine · 2026Article
- Mediating role of rehabilitation self-efficacy in the relationship between stress perception and depression among Chinese patients with stroke during the recovery period.Scientific reports · 2026Article
- The Impact of Comorbidities on Functional Outcomes After Rehabilitation in Stroke Patients.Healthcare (Basel, Switzerland) · 2026Article
- Exploring the Perspectives of People With Stroke on Exercise During Rehabilitation: A Qualitative Descriptive Study Focused on Aerobic Exercise Participation.Brain & NeuroRehabilitation · 2026Article
- Article
- Association Between Social Activities and Depression in Middle-Aged and Older Stroke Patients.International journal of behavioral medicine · 2026Article
- Development of a Risk Prediction Model for Post-Stroke Functional Recovery Based on Clinical and Nursing Factors.Risk management and healthcare policy · 2026Article
- Machine learning combined with resting-state functional MRI to characterize functional brain differences in post-stroke depression.Frontiers in psychiatry · 2026Article
- Age, race, and education as moderators of post-stroke cognitive decline following dental care.Frontiers in stroke · 2026Article
- Factors associated with post-stroke depression one month after discharge among older patients based on Health Ecology Theory: a retrospective cross-sectional study of consecutive cases.Frontiers in psychiatry · 2026Article
- Early nursing interventions in post-stroke neurological rehabilitation: a comprehensive review of evidence predominantly from high-resource settings.Frontiers in neurology · 2026Review
- Predicting Post-Stroke Depression Risk in Elderly Patients Based on Machine Learning: A Retrospective Cohort Study Integrating Neuroimaging and Psychosocial Variables.Neuropsychiatric disease and treatment · 2026Article
- Effect of nurse-led rehabilitation enhancement program on self-efficacy, functional ability, quality of life and perceived dependence among stroke survivors: A quasi-experimental study.Journal of education and health promotion · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPost-stroke depression (PSD) is a frequent problem in stroke patients, affecting their rehabilitation process and functional outcomes. Several studies have investigated the relationship between PSD and functional outcomes, but the results have been inconsistent.
objectiveThis systematic review of non-experimental studies aims to investigate the prevalence of post-stroke depression and the association between post-stroke depression and functional outcomes.
methodA search of PubMed, MEDLINE, Web of Science, and CINAHL Plus with Full Text was carried out from inception until January 2024. The literature was screened using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, with relevant papers included. We extracted data from non-experimental studies that examined associations between PSD and functional outcomes. The Joanna Briggs Institute for systematic reviews was used for critical appraisal.
resultsTwenty-one studies met the study criteria, including sixteen cohort studies, four cross-sectional studies, and one case-control study. PSD prevalences ranged from 12.2% to 32.2% in the first two weeks, 17.9 to 35.5% in the first month, and 10.4% to 32.0% in the third month following a stroke. Functional outcomes were evaluated in four domains: degree of dependence, basic activity of daily living, instrumental activity of daily living, and physical and cognitive function. Significant associations between PSD and functional outcomes were identified after controlling potential factors such as age, comorbidities, and stroke severity. PSD had negative associations with functional outcomes in all four measure domains from one month to five years after a stroke. Depression treatment showed positive results on functional outcomes in stroke patients.
conclusionPSD prevalence was high in the first three months after stroke. PSD is significantly associated with poor functional outcomes. PSD assessment and management should be performed on a frequent basis in the early stages of stroke to achieve the best possible functional recovery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.