Evidence map›Paper›PMID 39171915›Full record

ArticleJournal of bacteriology2024

Glycerol metabolism contributes to competition by oral streptococci through production of hydrogen peroxide.

Zachary A Taylor, Ping Chen, Payam Noeparvar, Danniel N Pham, Alejandro R Walker, Todd Kitten, Lin Zeng

Abstract read
In one paragraph

Article in Journal of bacteriology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. AJournal of bacteriology · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Systematic analysis of the glucose-PTS inApplied and environmental microbiology · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Zachary A Taylor *Department of Oral Biology, University of Florida College of Dentistry, Gainesville, Florida, USA.ORCID 0000-0001-8727-6197
Ping Chen *Department of Oral Biology, University of Florida College of Dentistry, Gainesville, Florida, USA.
Payam NoeparvarDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, Florida, USA.
Danniel N PhamDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, Florida, USA.ORCID 0009-0007-8961-1631
Alejandro R WalkerDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, Florida, USA.ORCID 0000-0002-5839-6584
Todd KittenPhilips Institute for Oral Health Research, Virginia Commonwealth University School of Dentistry, Richmond, Virginia, USA.ORCID 0000-0001-6097-7583
Lin ZengDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, Florida, USA.ORCID 0000-0002-9269-2707

Funding

GENE REGULATION AND PHYSIOLOGY OF STREPTOCOCCUS MUTANSR01DE012236 · NIDCR · UNIVERSITY OF ROCHESTER · PI Lin Zeng · 1997 to 2026
$8.5M
Comprehensive Training Program in Oral BiologyT90DE021990 · NIDCR · UNIVERSITY OF FLORIDA · PI Jose A Lemos · 2011 to 2026
$8.2M
HHS | NIH | National Institute of Dental and Craniofacial Research (NIDCR) DE12236NIDCR NIH HHS R01 DE012236NIDCR NIH HHS T90 DE021990
6 · The paper itself

Abstract

As a biological byproduct from both humans and microbes, glycerol's contribution to microbial homeostasis in the oral cavity remains understudied. In this study, we examined glycerol metabolism by IMPORTANCE: Glycerol is an abundant carbohydrate in the oral cavity. However, little is understood regarding the metabolism of glycerol by commensal streptococci, some of the most abundant oral bacteria. This was in part because most streptococci cannot grow on glycerol as the sole carbon source. In this study, we show that

Indexed as

Bacterial ProteinsGene Expression Regulation, BacterialGlycerolHydrogen PeroxideMouthStreptococcus mutansBiofilmsHumansStreptococcus sanguisBacterial ProteinsGlycerolHydrogen Peroxidecompetitiondental cariesglycerol metabolismhydrogen peroxidephosphotransferase system (pts)Streptococcus sanguinis

Identifiers

PMID39171915
PMCPMC11411925

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.