ArticleJournal of the Pediatric Infectious Diseases Society2024
Racial and Ethnic Disparities in Testing of Hepatitis C Virus-Exposed Children Across the United States.
Article in Journal of the Pediatric Infectious Diseases Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Hepatitis C Virus Testing in Perinatally Exposed Children.JAMA network open · 2026Article
- Cost-Effectiveness of One-Time Universal Childhood Hepatitis C Screening in the United States.Journal of the Pediatric Infectious Diseases Society · 2026Article
- Disparities in Linkage to Care Among Children With Hepatitis C Virus in the United States.Pediatrics · 2025Article
- A Call to Pediatricians: How Can We Improve HCV Testing in Perinatally Exposed Infants?Pediatrics · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundDespite rising hepatitis C virus (HCV) prevalence among pregnant individuals in the United States, HCV testing among exposed infants remains low. Although recent guidelines recommend early ribonucleic acid (RNA) testing for HCV-exposed children to help improve testing rates, national studies describing factors associated with HCV testing and the type of testing completed are lacking.
methodsIn this retrospective national study, we characterized HCV testing and care among HCV-exposed infants born between 2010 and 2020 captured in the electronic health record-based TriNetX Research Network. We analyzed factors associated with appropriate HCV testing completion (negative or positive HCV RNA testing or negative HCV antibody testing at any age through study end in 2022) and with RNA compared with antibody testing using univariable and multivariable logistic regression with clustered standard errors by healthcare organization.
resultsOf 8516 HCV-exposed children, 45.8% completed any HCV testing and 42.1% completed appropriate testing (25% of whom had RNA testing only). A total of 182 (5.1% of appropriately tested children) had evidence of HCV infection. Of 104 treatment-eligible children, 14.4% were treated. Black (odds ratio [OR]: 0.38, 95% confidence interval [CI]: 0.26-0.55), Asian/Pacific Islander (OR: 0.06, 95% CI: 0.03-0.11), and Hispanic/Latinx (OR: 0.56, 95% CI: 0.36-0.88) children had lower odds of appropriate testing compared with White and non-Hispanic/Latinx children.
conclusionsFewer than half of HCV-exposed children in this national sample were tested for HCV, with lower testing odds among Black, Asian/Pacific Islander, and Hispanic/Latinx children. Substantial work to increase testing and treatment and decrease disparities in testing among HCV-exposed children is needed to help reach US HCV elimination goals.
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