Evidence map›Paper›PMID 39171478›Full record

ArticleCurrent HIV research2024

Does Maternal HIV Infection Affect Neonatal Outcomes?

Mohammadreza Zarkesh, Farzaneh Kermani, Mohammad Bolbolian Ghalibaf, Azam Orooji, Raheleh Moradi

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Article in Current HIV research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Mohammadreza ZarkeshMaternal, Fetal and Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Farzaneh KermaniHealth Information Technology Department, School of Allied Medical Sciences, Semnan University of Medical Sciences, Semnan, Iran.
Mohammad Bolbolian GhalibafDepartment of Statistics, Faculty of Mathematics and Computer Sciences, Hakim Sabzevari University, Sabzevar, Iran.
Azam OroojiDepartment of Medical Biotechnology, School of Medicine, North Khorasan University of Medical Science (NKUMS), Bojnourd, Iran.
Raheleh MoradiReproductive Health, Maternal, Fetal and Neonatal Research Center, Institute of Family Health, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPregnancy among women infected with HIV is classified as a high-risk pregnancy. While previous research has indicated an elevated likelihood of preterm birth, low birth weight, and early gestational age in infants born to mothers with HIV, the correlation between maternal HIV infection and different neonatal results remains unclear.

objectiveThis study aims to investigate the impact of maternal HIV infection on after-birth neonatal outcomes using machine learning (ML) and statistical methods.

methodsA case-control study is conducted through a three-stage process: Initially, the outcomes among newborns from HIV-positive mothers are identified through a combination of literature review and expert survey. Subsequently, data are paired at a 1:2 ratio based on gestational age with infants from HIV-positive mothers (n=48) compared to HIV-negative mothers (n=96) as the control group. Finally, filter, wrapper and embedded based feature selection techniques are applied to identify outcomes that exhibit significant differences between the two groups. feature selection techniques are applied to identify outcomes that exhibit significant differences between the two groups. OUTCOMES:

resultsThe statistical analysis showed that the rate of addiction among HIV-positive mothers is higher than that of the HIV-negative group. The need for mechanical ventilation and duration of ventilator-assisted breathing in infants born to HIV-positive mothers are significantly higher than in infants born to HIV-negative mothers. Moreover, based on feature selection methods, increasing the need for mechanical ventilation and reducing surfactant administration were two important outcomes.

conclusionTo investigate the impact of maternal HIV infection on neonatal outcomes, various statistical and machine learning-based feature selection techniques were implemented, and the results showed that the presented methods can be utilized to examine the potential impacts of different diseases contracted by the mother on the infant.

Indexed as

HIV InfectionsPregnancy Complications, InfectiousAdultCase-Control StudiesFemaleHumansInfant, NewbornInfectious Disease Transmission, VerticalMachine LearningMalePregnancyPregnancy OutcomePremature BirthAntiretroviral therapyHIV/AIDSinfectious disease transmissionmachine learning.prenatal carewrapper feature selection

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.