Evidence map›Paper›PMID 39171477›Full record

ReviewCurrent drug delivery2026

Nanocrystals: Versatile Platform for Traditional Chinese Medicine Delivery.

Chuanyu Ren, Yue Gao, Yeqi Huang, Siyuan Peng, Xuan Zhang, Weijie Wang, Chuanbin Wu, Xin Pan, Zhengwei Huang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current drug delivery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. High Flavonoid Content inPharmaceutical nanotechnology · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chuanyu RenCollege of Pharmacy, Jinan University, Guangzhou 511443, Guangdong, PR China.
Yue GaoCollege of Pharmacy, Jinan University, Guangzhou 511443, Guangdong, PR China.
Yeqi HuangCollege of Pharmacy, Jinan University, Guangzhou 511443, Guangdong, PR China.
Siyuan PengSchool of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, Guangdong, PR China.
Xuan ZhangCollege of Pharmacy, Northern Jiangsu People's Hospital, Jiangsu, China.
Weijie WangDepartment of Rheumatology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310005, China.
Chuanbin WuCollege of Pharmacy, Jinan University, Guangzhou 511443, Guangdong, PR China.
Xin PanSchool of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, Guangdong, PR China.
Zhengwei HuangCollege of Pharmacy, Jinan University, Guangzhou 511443, Guangdong, PR China.

Funding

General Program of Administration of Traditional Chinese Medicine of Guangdong Province China 20241071National Natural Science Foundation of China 82373800, 82104070
6 · The paper itself

Abstract

The medicinal value of Chinese medicines has been recognized since ancient times, and they have also been used to treat various diseases. However, in-depth studies on the active ingredients of Chinese medicines have shown that many of them suffer from poor water-solubility, stability, and bioavailability, which has severely limited their further development. The advent of nanomedicine represents a novel direction and paradigm for addressing these challenges. Particularly, within the framework of nanocrystal technology, enhancements in the water solubility, stability, and bioavailability of Chinese medicines are expected to significantly improve the therapeutic efficiency. This advancement also holds promise for unlocking new therapeutic capabilities. Nanocrystals offer significant advantages in oral, intravenous, intranasal and targeted delivery. The drug loading principle is "all in one", with hydrophobic-drug-in and hydrophilic-drug-out and stabilization by amphiphilic agents. Nanocrystal technology in traditional Chinese medicine (TCM) holds extensive application potential. Continuous refinement of preparation techniques, sound safety assessments, and the promotion of large-scale production are anticipated to augment its pivotal role in TCM formulations, thereby creating novel opportunities for clinical drug therapy.

Indexed as

Drug Delivery SystemsDrugs, Chinese HerbalMedicine, Chinese TraditionalNanoparticlesAnimalsBiological AvailabilityHumansSolubilityDrugs, Chinese Herbaldrug deliverynano-Chinese medicineNanocrystalnanotechnologytraditional Chinese medicinetraditional Chinese medicine preparations.

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.