Evidence map›Paper›PMID 39171134›Full record

ArticleEuropean heart journal. Case reports2024

Home inotrope therapy in chronic stimulant-induced cardiomyopathy: a case series.

Max Joseph, Sejal Batra, Wali Kamran, Kelsey Barrett, Barbara Ebert, Ahmed Nassar, Timothy Misselbeck, Nael Hawwa

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in European heart journal. Case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Max JosephLehigh Valley Heart and Vascular Institute, Lehigh Valley Health Network, 1250 S Cedar Crest Blvd #300, Allentown, PA 18103, USA.
Sejal BatraLehigh Valley Heart and Vascular Institute, Lehigh Valley Health Network, 1250 S Cedar Crest Blvd #300, Allentown, PA 18103, USA.
Wali KamranLehigh Valley Heart and Vascular Institute, Lehigh Valley Health Network, 1250 S Cedar Crest Blvd #300, Allentown, PA 18103, USA.
Kelsey BarrettLehigh Valley Heart and Vascular Institute, Lehigh Valley Health Network, 1250 S Cedar Crest Blvd #300, Allentown, PA 18103, USA.
Barbara EbertLehigh Valley Heart and Vascular Institute, Lehigh Valley Health Network, 1250 S Cedar Crest Blvd #300, Allentown, PA 18103, USA.
Ahmed NassarLehigh Valley Heart and Vascular Institute, Lehigh Valley Health Network, 1250 S Cedar Crest Blvd #300, Allentown, PA 18103, USA.
Timothy MisselbeckLehigh Valley Heart and Vascular Institute, Lehigh Valley Health Network, 1250 S Cedar Crest Blvd #300, Allentown, PA 18103, USA.
Nael HawwaLehigh Valley Heart and Vascular Institute, Lehigh Valley Health Network, 1250 S Cedar Crest Blvd #300, Allentown, PA 18103, USA.ORCID https://orcid.org/0009-0002-1370-8342

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients with chronic stimulant-induced cardiomyopathy presenting with cardiogenic shock can be stabilized with conventional measures. However, their management post-stabilization has not been well described and poses unique challenges: (i) less chance of myocardial recovery compared to acute stimulant-induced cardiomyopathy, (ii) psychosocial barriers to left ventricular assist device (LVAD) and heart transplantation, and (iii) concern for use of peripherally inserted central catheter for home inotrope in those with a history of substance abuse. Case summary: Three patients with chronic stimulant-induced cardiomyopathy were admitted with cardiogenic shock progressing to Society for Cardiovascular Angiography & Interventions stage D or E. They were stabilized with inotrope and/or biventricular mechanical circulatory support. Long-term home inotrope was used as either a bridge to LVAD, reverse remodelling, or stabilization. Discussion: Home inotrope should be viewed as an option in chronic stimulant-induced cardiomyopathy on a case-by-case basis. It can buy time to allow for myocardial stabilization or recovery through goal-directed medical therapy and stimulant cessation. It can also serve as a 'psychosocial stress test' for future consideration of advanced heart failure therapies.

Indexed as

Cardiogenic shockCase reportHome inotropeMethamphetamine

Identifiers

PMID39171134
PMCPMC11336994

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.