Evidence map›Paper›PMID 39170956›Full record

ArticleJACC. Basic to translational science2024

Clopidogrel-Mediated P2Y

Luis Ortega-Paz, Francesco Franchi, Fabiana Rollini, Mattia Galli, Latonya Been, Ghussan Ghanem, Awss Shalhoub, Tiffany Ossi, Andrea Rivas, Xuan Zhou and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Basic to translational science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Luis Ortega-PazDivision of Cardiology, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA.
Francesco FranchiDivision of Cardiology, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA.
Fabiana RolliniDivision of Cardiology, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA.
Mattia GalliDivision of Cardiology, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA.
Latonya BeenDivision of Cardiology, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA.
Ghussan GhanemDivision of Cardiology, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA.
Awss ShalhoubDivision of Cardiology, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA.
Tiffany OssiDivision of Cardiology, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA.
Andrea RivasDivision of Cardiology, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA.
Xuan ZhouDivision of Cardiology, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA.
Andres M PinedaDivision of Cardiology, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA.
Siva SuryadevaraDivision of Cardiology, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA.
Daniel SofferDivision of Cardiology, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA.
Martin M ZenniDivision of Cardiology, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA.
Madeline K MahowaldDivision of Cardiology, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA.
Taimour LangaeeDepartment of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy University of Florida, Gainesville, Florida, USA.
Joseph A JakubowskiThe Indiana Biosciences Research Institute, Indianapolis, Indiana, USA.
Larisa H CavallariDepartment of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy University of Florida, Gainesville, Florida, USA.
Dominick J AngiolilloDivision of Cardiology, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This prospective ex vivo and in vitro pharmacodynamic (PD)/pharmacokinetic investigation was conducted in patients with diabetes mellitus with (n = 31) and without chronic kidney disease (n = 30). PD assessments included platelet reactivity index, maximum platelet aggregation, and P2Y

Indexed as

chronic kidney diseaseclopidogrelcoronary artery diseasediabetes mellituspharmacodynamicpharmacokineticplatelets

Identifiers

PMID39170956
PMCPMC11334417

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.