Evidence map›Paper›PMID 39170700›Full record

ArticleFrontiers in pharmacology2024

Schisandrin C enhances type I IFN response activation to reduce tumor growth and sensitize chemotherapy through antitumor immunity.

Huijie Yang, Xiaoyan Zhan, Jia Zhao, Wei Shi, Tingting Liu, Ziying Wei, Hui Li, Xiaorong Hou, Wenqing Mu, Yuanyuan Chen and 5 more

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Huijie Yang *School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Xiaoyan Zhan *China Military Institute of Chinese Materia, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Jia Zhao *China Military Institute of Chinese Materia, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Wei ShiChina Military Institute of Chinese Materia, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Tingting LiuChina Military Institute of Chinese Materia, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Ziying WeiChina Military Institute of Chinese Materia, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Hui LiSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Xiaorong HouChina Military Institute of Chinese Materia, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Wenqing MuChina Military Institute of Chinese Materia, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Yuanyuan ChenChina Military Institute of Chinese Materia, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Congyang ZhengChina Military Institute of Chinese Materia, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Zhongxia WangDepartment of Nutrition, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Shengli WeiSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Xiaohe XiaoChina Military Institute of Chinese Materia, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Zhaofang BaiChina Military Institute of Chinese Materia, The Fifth Medical Center of PLA General Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the advancing comprehension of immunology, an increasing number of immunotherapies are being explored and implemented in the field of cancer treatment. The cGAS-STING pathway, a crucial element of the innate immune response, has been identified as pivotal in cancer immunotherapy. We evaluated the antitumor effects of

Indexed as

antitumor immunityCD8+ T cellcGAS-STING pathwayNK cellSchisandrin Ctype I interferon

Identifiers

PMID39170700
PMCPMC11337024

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.