Evidence map›Paper›PMID 39170101›Full record

ReviewInternational journal of nanomedicine2024

Surface Engineering of Magnetic Iron Oxide Nanoparticles for Breast Cancer Diagnostics and Drug Delivery.

Mengjie Xie, Fansu Meng, Panpan Wang, Alicia Marcelina Díaz-García, Marina Parkhats, Ralph Santos-Oliveira, Mulazim Hussain Asim, Nazish Bostan, Honghui Gu, Lina Yang and 4 more

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Iron-Based Nanoparticles as Delivery Tools.Pharmaceuticals (Basel, Switzerland) · 2026
    Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Iron Oxide Nanoparticle-Based TNanomaterials (Basel, Switzerland) · 2024
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mengjie Xie *State Key Laboratory of Bioactive Molecules and Druggability Assessment, Jinan University International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Ministry of Education (MOE) of China / Guangdong Key Laboratory of Traditional Chinese Medicine Informatization / International Science and Technology Cooperation Base of Guangdong Province/School of Pharmacy, Jinan University, Guangzhou, Guangdong, 510632, People's Republic of China.
Fansu Meng *Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine, Zhongshan, Guangdong, 528400, People's Republic of China.
Panpan Wang *The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, 510632, People's Republic of China.
Alicia Marcelina Díaz-GarcíaBioinorganic Laboratory, Faculty of Chemistry, University of Havana, Havana, 1400, Cuba.ORCID 0000-0002-1527-8174
Marina ParkhatsB. I. Stepanov Institute of Physics, National Academy of Sciences of Belarus, Minsk, 220072, Belarus.
Ralph Santos-OliveiraBrazilian Nuclear Energy Commission, Nuclear Engineering Institute, Laboratory of Nanoradiopharmacy and Synthesis of New Radiopharmaceuticals, Rio de Janeiro, RJ, 21941906, Brazil.
Mulazim Hussain AsimCollege of Pharmacy, University of Sargodha, Punjab, 40100, Pakistan.ORCID 0000-0003-1910-9615
Nazish BostanDepartment of Pharmaceutics, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan.
Honghui GuShenzhen Traditional Chinese Medicine Hospital, Shenzhen, Guangdong, 518033, People's Republic of China.
Lina YangShenzhen Traditional Chinese Medicine Hospital, Shenzhen, Guangdong, 518033, People's Republic of China.
Qi LiShenzhen Traditional Chinese Medicine Hospital, Shenzhen, Guangdong, 518033, People's Republic of China.
Zhenjiang YangShenzhen Traditional Chinese Medicine Hospital, Shenzhen, Guangdong, 518033, People's Republic of China.
Haibiao LaiZhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine, Zhongshan, Guangdong, 528400, People's Republic of China.
Yu CaiState Key Laboratory of Bioactive Molecules and Druggability Assessment, Jinan University International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Ministry of Education (MOE) of China / Guangdong Key Laboratory of Traditional Chinese Medicine Informatization / International Science and Technology Cooperation Base of Guangdong Province/School of Pharmacy, Jinan University, Guangzhou, Guangdong, 510632, People's Republic of China.ORCID 0000-0002-8532-7816

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Data published in 2020 by the International Agency for Research on Cancer (IARC) of the World Health Organization show that breast cancer (BC) has become the most common cancer globally, affecting more than 2 million women each year. The complex tumor microenvironment, drug resistance, metastasis, and poor prognosis constitute the primary challenges in the current diagnosis and treatment of BC. Magnetic iron oxide nanoparticles (MIONPs) have emerged as a promising nanoplatform for diagnostic tumor imaging as well as therapeutic drug-targeted delivery due to their unique physicochemical properties. The extensive surface engineering has given rise to multifunctionalized MIONPs. In this review, the latest advancements in surface modification strategies of MIONPs over the past five years are summarized and categorized as constrast agents and drug delivery platforms. Additionally, the remaining challenges and future prospects of MIONPs-based targeted delivery are discussed.

Indexed as

Breast NeoplasmsMagnetic Iron Oxide NanoparticlesAnimalsAntineoplastic AgentsDrug Delivery SystemsFemaleHumansMagnetite NanoparticlesSurface PropertiesTumor MicroenvironmentAntineoplastic AgentsMagnetite NanoparticlesInorganic NanomaterialsNanopreparationsOrganic NanomaterialsSurface EngineeringTargeted Delivery

Identifiers

PMID39170101
PMCPMC11338174

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.