Evidence map›Paper›PMID 39169749›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2025

Imaging the 5-HT

Khanum Ridler, Gaia Rizzo, Ethan S Burstein, Anton Forsberg Morén, Vladimir Stepanov, Christer Halldin, Eugenii A Rabiner

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Khanum RidlerInvicro, London, UK.ORCID 0009-0005-1809-058X
Gaia RizzoInvicro, London, UK.
Ethan S BursteinACADIA Pharmaceuticals Inc., San Diego, CA, USA.
Anton Forsberg MorénDepartment of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden.
Vladimir StepanovDepartment of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden.
Christer HalldinDepartment of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden.
Eugenii A RabinerInvicro, London, UK.ORCID 0000-0003-3612-6687

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two complimentary techniques were used to estimate occupancy of pimavanserin (a selective 5-HT

Indexed as

BrainCarbon RadioisotopesReceptor, Serotonin, 5-HT2AReceptor, Serotonin, 5-HT2CSerotonin 5-HT2 Receptor AgonistsSerotonin 5-HT2 Receptor AntagonistsAnimalsBenzylaminesDrug Inverse AgonismMacaca fascicularisPhenethylaminesPiperidinesPositron-Emission TomographyUreaBenzylaminesCarbon RadioisotopesCimbi-36PhenethylaminespimavanserinPiperidinesReceptor, Serotonin, 5-HT2AReceptor, Serotonin, 5-HT2CSerotonin 5-HT2 Receptor AgonistsSerotonin 5-HT2 Receptor AntagonistsUrea5-HT2A5-HT2Cpimavanserinpositron emission tomography and serotonin

Identifiers

PMID39169749
PMCPMC11800257

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.