Evidence map›Paper›PMID 39169339›Full record

ArticleBMC oral health2024

When is surgical intervention needed in oral and maxillofacial space infection patients? A retrospective case control study in 46 patients.

Yimin Liu, Hanyi Zhu, Xin Bao, Yingyi Qin, Zhiyuan He, Lingyan Zheng, Huan Shi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yimin Liu *College of Stomatology, Shanghai Jiao Tong University, Shanghai, China.
Hanyi Zhu *College of Stomatology, Shanghai Jiao Tong University, Shanghai, China.
Xin BaoCollege of Stomatology, Shanghai Jiao Tong University, Shanghai, China.
Yingyi QinDepartment of Health Statistics, Second Military Medical University, Shanghai, China.
Zhiyuan HeDepartment of Oral Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, No. 639, ZhiZaoJu Road, Shanghai, 200011, China.
Lingyan ZhengCollege of Stomatology, Shanghai Jiao Tong University, Shanghai, China. zhenglingyan73@163.com.
Huan ShiCollege of Stomatology, Shanghai Jiao Tong University, Shanghai, China. shihuan1312@163.com.

Funding

Biological Sample Bank Project of Ninth People's Hospital Affiliated with Shanghai Jiao Tong University School of Medicine YBKB202107, YBYB202212National Natural Science Foundation of China 82174041
6 · The paper itself

Abstract

objectivePatients with mild oral and maxillofacial space infection (OMSI) usually need only antimicrobial therapy. However, surgical intervention is eventually needed after using antibiotics for a period. The objective of this study was to explore the risk factors for drug therapy failure in OMSI. SUBJECTS AND

methodsA retrospective case‒control study was designed. From August 2020 to September 2022, patients at Shanghai Jiao Tong University Affiliated Ninth People's Hospital who were diagnosed with OMSI were retrospectively reviewed. The outcome variable was surgical intervention after the use of antibiotics. We collected common biological factors, including demographic characteristics, routine blood test results, C-reactive protein (CRP) levels and composite indicators, such as neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR). The χ2 test and binary logistic regression were used to examine the association between biological factors and the outcome variable.

resultsForty-six patients were included in this study. Further surgical intervention was needed in 20 patients (43.5%). The NLR showed a significant association with further surgical drainage (p = 0.01). A binary logistic regression equation was found by using stepwise regression based on the Akaike information criterion (R2 = 0.443), which was associated with sex (odds ratio [OR], 0.216; p = 0.092), NLR (OR, 1.258; p = 0.045), red blood cell (RBC) count (OR, 4.372; p = 0.103) and monocyte (MONO) count (OR, 9.528, p = 0.023). Receiver operating characteristic analysis produced an area under the curve for NLR of 0.725 (p = 0.01) and for the binary logistic regression model of 0.8365 (p < 0.001).

conclusionSurgical interventions are needed in some mild OMSI patients when antimicrobial therapy fails to stop the formation of abscesses. The binary logistic regression model shows that NLR can be used as an ideal prognostic factor to predict the outcome of antimicrobial therapy and the possibility of requiring surgical intervention. STATEMENT OF CLINICAL RELEVANCE: Using simple, inexpensive, and easily achieved biological parameters (such as routine blood test results) and composite indicators calculated by them (such as NLR) to predict whether surgical intervention is needed in the future provides a reference for clinical doctors and enables more cost-effective and efficient diagnosis and treatment.

Indexed as

Anti-Bacterial AgentsAdultAgedCase-Control StudiesC-Reactive ProteinDrainageFemaleFocal Infection, DentalHumansLymphocyte CountMaleMiddle AgedNeutrophilsRetrospective StudiesRisk FactorsYoung AdultAnti-Bacterial AgentsC-Reactive ProteinNeutrophil to lymphocyte ratioOral and maxillofacial space infectionPrognostic factorSurgical intervention

Identifiers

PMID39169339
PMCPMC11340201

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.