Evidence map›Paper›PMID 39169287›Full record

Observational studyBMC infectious diseases2024

Prevalence and risk factors of post-acute sequelae of SARS-CoV-2 (PASC) among veterans in the airborne hazards and open burn pit registry: a prospective, observational, nested study.

Sherilynn M Phen, Nisha Jani, Jacquelyn C Klein-Adams, Duncan S Ndirangu, Azizur Rahman, Michael J Falvo

Abstract readObservational Study
In one paragraph

Observational study in BMC infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sherilynn M PhenAirborne Hazards and Burn Pits Center of Excellence, VA New Jersey Health Care System, East Orange, New Jersey, USA.
Nisha JaniAirborne Hazards and Burn Pits Center of Excellence, VA New Jersey Health Care System, East Orange, New Jersey, USA.
Jacquelyn C Klein-AdamsAirborne Hazards and Burn Pits Center of Excellence, VA New Jersey Health Care System, East Orange, New Jersey, USA.
Duncan S NdiranguAirborne Hazards and Burn Pits Center of Excellence, VA New Jersey Health Care System, East Orange, New Jersey, USA.
Azizur RahmanAirborne Hazards and Burn Pits Center of Excellence, VA New Jersey Health Care System, East Orange, New Jersey, USA.
Michael J FalvoAirborne Hazards and Burn Pits Center of Excellence, VA New Jersey Health Care System, East Orange, New Jersey, USA. Michael.Falvo@va.gov.

Funding

ACTIV Integration of Host-targeting Therapies for COVID-19 Administrative Coordinating CenterOT2HL156812 · NHLBI · RESEARCH TRIANGLE INSTITUTE · PI NOLEN, TRACY L, THOMAS, SONIA M · 2020 to 2024
$1270.7M
NHLBI NIH HHS OT2 HL156812
6 · The paper itself

Abstract

backgroundVeterans have unique military risk factors and exposures during deployment that may augment their risk of post-acute sequelae of SARS-CoV-2 (PASC). The purpose of this study is to identify potential risk factors for PASC among Veterans in the national Airborne Hazards and Open Burn Pit Registry (AHOBPR).

methodsThis prospective observational study consisted of a semi-structured interview conducted via phone or videoconference from November 2021 to December 2022 among a stratified random sample of deployed Veterans nested within the national AHOBPR with laboratory-confirmed SARS-CoV-2 infection. PASC was defined as persistent new-onset symptoms lasting more than 2 months after initial SARS-CoV-2 infection. Deployment history, airborne hazards exposure and symptoms were obtained from the AHOBPR self-assessment questionnaire completed prior to SARS-CoV-2 infection (past). Post-infection symptoms and health behaviors obtained at study interview (present) were used to test the hypothesis that deployment experience and exposure increases the risk for PASC.

resultsFrom a sample of 212 Veterans, 149 (70%) met criteria for PASC with a mean age of 47 ± 8.7 years; 73 (49%) were women and 76 (51%) were men, and 129 (82.6%) continued to experience persistent symptoms of SARS-CoV-2 (596.8 ± 160.4 days since initial infection). Neither exposure to airborne hazards (OR 0.97, CI 0.92-1.03) or to burn pits (OR 1.00, CI 0.99-1.00) augmented risk for PASC.

conclusionsPASC is highly common among Veterans enrolled in the AHOBPR, but we did not observe any unique military risk factors (e.g., airborne hazards exposure) that augmented the risk of PASC. Our findings may provide guidance to clinicians in the VHA network to administer appropriate care for Veterans experiencing PASC.

Indexed as

Post-Acute COVID-19 SyndromeRegistriesVeteransAdultFemaleHumansMaleMiddle AgedOpen Waste BurningPrevalenceProspective StudiesRisk FactorsSARS-CoV-2United StatesCOVID-19Environmental exposure; veterans healthOpen waste burningPost-acute COVID-19 syndromePost-acute sequelae of SARS-CoV-2 (PASC)post-COVID conditionsVeterans health

Identifiers

PMID39169287
PMCPMC11337853

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.