Evidence map›Paper›PMID 39169179›Full record

ArticleNature2024

Lysosomes drive the piecemeal removal of mitochondrial inner membrane.

Akriti Prashar, Claudio Bussi, Antony Fearns, Mariana I Capurro, Xiaodong Gao, Hiromi Sesaki, Maximiliano G Gutierrez, Nicola L Jones

Abstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed.

  1. Article
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  15. A PI(3,5)PNature communications · 2026
    Article
  16. Article
  17. Article
  18. Review
  19. Relationship between different modes of death and premature ovarian insufficiency: a literature review.Apoptosis : an international journal on programmed cell death · 2026
    Review
  20. Review

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Akriti PrasharCell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Claudio Bussi *Host-Pathogen Interactions in Tuberculosis Laboratory, The Francis Crick Institute, London, UK.ORCID 0000-0002-9396-9042
Antony Fearns *Host-Pathogen Interactions in Tuberculosis Laboratory, The Francis Crick Institute, London, UK.ORCID 0000-0001-9937-8545
Mariana I CapurroCell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0002-4560-7186
Xiaodong GaoCell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Hiromi SesakiDepartment of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Maximiliano G GutierrezHost-Pathogen Interactions in Tuberculosis Laboratory, The Francis Crick Institute, London, UK.ORCID 0000-0003-3199-0337
Nicola L JonesCell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada. Nicola.jones@sickkids.ca.ORCID 0000-0001-5495-0739

Funding

Structure, Turnover and Safeguard of MitochondriaR35GM144103 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Hiromi Sesaki · 2022 to 2026
$2.8M
Cancer Research UK CC2081NIGMS NIH HHS R35 GM144103Wellcome Trust CC2081Wellcome Trust FC001092
6 · The paper itself

Abstract

Mitochondrial membranes define distinct structural and functional compartments. Cristae of the inner mitochondrial membrane (IMM) function as independent bioenergetic units that undergo rapid and transient remodelling, but the significance of this compartmentalized organization is unknown

Indexed as

LysosomesMitochondriaMitochondrial MembranesAnimalsAutophagyCalciumCell CompartmentationCytosolHomeostasisHumansMiceMitochondrial DynamicsOxidative StressReactive Oxygen SpeciesTransient Receptor Potential ChannelsVoltage-Dependent Anion Channel 1CalciumMCOLN1 protein, humanMcoln1 protein, mouseReactive Oxygen SpeciesTransient Receptor Potential ChannelsVoltage-Dependent Anion Channel 1

Identifiers

PMID39169179
PMCPMC7616637

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.