ArticleScientific reports2024
Shift work and non-alcoholic fatty liver disease in young, healthy workers.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Shift work and metabolic dysfunction-associated steatotic liver disease: a systematic review of observational studies.International archives of occupational and environmental health · 2025Pooled it
- Molecular mechanisms and pathogenesis of MASH.Nature · 2026Review
- Circadian and behavioral timing in MASLD: a systematic review of human observational studies.EClinicalMedicine · 2026Article
- Diurnal Light Exposure and Rest-Activity Rhythms in Relation to MASLD: Insights From 2 Nationwide Cohort Studies.The Journal of clinical endocrinology and metabolism · 2026Article
- Modeling the dynamics of hepatic metabolism: the predominance of 12-hour rhythmicity in metabolic adaptation.Cellular and molecular life sciences : CMLS · 2026Article
- Association between occupational noise exposure and metabolic dysfunction-associated fatty liver disease: the mediating role of body mass index in automotive manufacturing workers.Frontiers in public health · 2026Article
- Association of Shift Work, Health Behaviors, and Socioeconomic Status with Diabesity in over 53,000 Spanish Employees.Journal of clinical medicine · 2025Article
- Associations Between Shift Work, Sociodemographic and Lifestyle Characteristics, Body Measurements, and MASLD.Life (Basel, Switzerland) · 2025Article
- Circadian Deregulation: Back Facing the Sun Toward Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Development.Nutrients · 2024Review
- Liver-gut axis signaling regulates circadian energy metabolism in shift workers.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024Article
- The association between working hours and working type with non-alcoholic fatty liver disease: results from the NHANES 1999-2014.Frontiers in endocrinology · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-alcoholic fatty liver disease (NAFLD) is a relatively common disease, and preventing its occurrence is important for both individual health and reducing social costs. Shift work is reported to have several negative effects on health. An association has been observed between NAFLD and both sleep time and quality; however, this association remains unclear in night shift workers. We aimed to evaluate the relationship between shift work and the incidence of NAFLD. Overall, 45,149 Korean workers without NAFLD were included at baseline. NAFLD was defined as the presence of a fatty liver observed on ultrasonography without excessive alcohol use. incidence rate ratios for incident NAFLD were estimated using negative binomial regression according to age groups (20s, 30s, 40s, and 50s). In the 20s age group, shift work showed a significant incidence rate ratio (IRR) for NAFLD in all models. After adjusting for all variables, the IRR (95% confidence interval) was 1.24 (1.08-1.43) in the 20s age group. In their 20s, a significant association between shift work and incident NAFLD was consistently observed among women and workers with poor sleep quality. In this large-scale cohort study, shift work was significantly associated with the development of NAFLD among young workers in their 20s.
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