Evidence map›Paper›PMID 39169043›Full record

ArticleNature communications2024

Ultraselective Macrocycle Membranes for Pharmaceutical Ingredients Separation in Organic Solvents.

Banan Alhazmi, Gergo Ignacz, Maria Di Vincenzo, Mohamed Nejib Hedhili, Gyorgy Szekely, Suzana P Nunes

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. In Situ Ptychographic X-ray Computed Tomography of Fully Hydrated Polyamide Membranes.Langmuir : the ACS journal of surfaces and colloids · 2026
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Banan Alhazmi *Environmental Science and Engineering Program, Biological and Environmental Science and Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.
Gergo Ignacz *Chemical Engineering Program, Physical Science and Engineering Division (PSE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.
Maria Di VincenzoEnvironmental Science and Engineering Program, Biological and Environmental Science and Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.ORCID 0000-0001-7773-7287
Mohamed Nejib HedhiliImaging and Characterization Laboratory, King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.
Gyorgy SzekelyEnvironmental Science and Engineering Program, Biological and Environmental Science and Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia. gyorgy.szekely@kaust.edu.sa.ORCID 0000-0001-9658-2452
Suzana P NunesEnvironmental Science and Engineering Program, Biological and Environmental Science and Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia. suzana.nunes@kaust.edu.sa.ORCID 0000-0002-3669-138X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Separations are core processes in the chemical and pharmaceutical industries. Several steps of fractionation and purification of multicomponent mixtures are required. Membrane technology can operate at fair temperatures, saving energy and processing sensitive compounds. However, breakthroughs require high stability and selectivity beyond those available today. Here, we propose membranes constituted by fully crosslinked crown ethers using interfacial polymerization. The 24 nm-thick nanofilms on robust porous supports exhibit up to 90% higher selectivity than commercially available membranes, with a 90% increase in solvent permeance. The membranes are tested with a complex mixture of structurally diverse solutes containing active pharmaceutical ingredients. The membranes are effective for the total retention and concentration of active pharmaceutical ingredients with molecular weights around 800 g mol

Indexed as

Membranes, ArtificialSolventsCrown EthersMacrocyclic CompoundsMolecular WeightPharmaceutical PreparationsPolymerizationPorosityCrown EthersMacrocyclic CompoundsMembranes, ArtificialPharmaceutical PreparationsSolvents

Identifiers

PMID39169043
PMCPMC11339351

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.