Evidence map›Paper›PMID 39168904›Full record

ArticleAAPS PharmSciTech2024

Antipsoriatic Effect of Silymarin NLCs Based Gel: In Vitro and In Vivo Activity.

Faijmahmad Momin, Vijay Kevlani, Shruti Rawal, Riya Patel, Sheetal Acharya, Shreeraj Shah

Abstract read
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In one paragraph

Article in AAPS PharmSciTech, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Faijmahmad MominDepartment of Pharmaceutical Technology, L.J. Institute of Pharmacy, L J University, LJ Campus, Near Sarkhej-Sanand Circle, Off. S.G. Road, Ahmedabad, 382 210, India.
Vijay KevlaniDepartment of Pharmaceutical Technology, L.J. Institute of Pharmacy, L J University, LJ Campus, Near Sarkhej-Sanand Circle, Off. S.G. Road, Ahmedabad, 382 210, India.
Shruti RawalDepartment of Pharmaceutical Technology, L.J. Institute of Pharmacy, L J University, LJ Campus, Near Sarkhej-Sanand Circle, Off. S.G. Road, Ahmedabad, 382 210, India.
Riya PatelDepartment of Pharmaceutical Technology, L.J. Institute of Pharmacy, L J University, LJ Campus, Near Sarkhej-Sanand Circle, Off. S.G. Road, Ahmedabad, 382 210, India.
Sheetal AcharyaDepartment of Pharmaceutical Technology, L.J. Institute of Pharmacy, L J University, LJ Campus, Near Sarkhej-Sanand Circle, Off. S.G. Road, Ahmedabad, 382 210, India.
Shreeraj ShahDepartment of Pharmaceutical Technology, L.J. Institute of Pharmacy, L J University, LJ Campus, Near Sarkhej-Sanand Circle, Off. S.G. Road, Ahmedabad, 382 210, India. shreeraj.shah@ljinstitutes.edu.in.ORCID http://orcid.org/0000-0002-8729-7104

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psoriasis is a chronic inflammatory disorder affecting over 100 million people, requires long-term therapy. Current treatments offer only symptomatic relief. However, phytoconstituents-based therapies like Silymarin (SLM) have shown promising effects. The study aims to develop, optimize, and evaluate a novel stable SLM NLC gel to improve anti-psoriatic activity by enhancing its permeability and retention into the dermal layer. SLM NLC formulation was prepared and optimized using 3

Indexed as

GelsParticle SizePsoriasisSilymarinAdministration, CutaneousAnimalsChemistry, PharmaceuticalDrug LiberationMaleMiceNanoparticlesSkinSkin AbsorptionGelsSilymarinlipid carriermicroemulsionpsoriasissilymarinsolid lipidstopical delivery

Identifiers

PMID39168904

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.