Evidence map›Paper›PMID 39168899›Full record

ArticleEuropean journal of applied physiology2025

Effects of ischemic pre-conditioning on electrically stimulated contractions.

Ruben Allois, Pasquale Pagliaro, Ermini Leonardo, Silvestro Roatta

Abstract read
In one paragraph

Article in European journal of applied physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ruben AlloisLaboratory of Integrative Physiology, Department of Neuroscience, University of Torino, c.so Raffaello 30, 10125, Turin, Italy.ORCID http://orcid.org/0000-0002-5381-6973
Pasquale PagliaroDepartment of Clinical and Biological Sciences, University of Torino, Turin, Italy.
Ermini LeonardoLaboratory of Integrative Physiology, Department of Neuroscience, University of Torino, c.so Raffaello 30, 10125, Turin, Italy.
Silvestro RoattaLaboratory of Integrative Physiology, Department of Neuroscience, University of Torino, c.so Raffaello 30, 10125, Turin, Italy. silvestro.roatta@unito.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIschemic pre-conditioning (IPC) offers protection against future ischemic events and may improve sports performance due to several mechanisms at local and systemic levels. This study investigates the local effects on muscle contractility in electrically induced muscle contractions, thus effectively excluding any uncontrolled change in the motor drive.

methodsTwenty-one subjects were divided into two groups: 12 subjects in the IPC group (3 × 5/5 min right arm ischemia/reperfusion; cuff pressure 250 mmHg) and 9 subjects in the SHAM group (same treatment at 20 mmHg). The adductor pollicis was contracted by supramaximal stimulation of the ulnar nerve with single pulses, trains of stimuli (5, 8, 10 and 12 Hz, 1-s duration) and bursts (4 pulses, 25 Hz), all separated by 5-s intervals. The stimulation sequence was delivered before and 15 and 30 min after IPC/SHAM treatment. The isometric contraction force, the superficial electromyographic signal, and tissue oxygenation were continuously monitored.

resultsA significant force decrease in time was observed at 8, 10 (p < 0.01) and 12 Hz (p < 0.05) along with a decrease in half-relaxation time in single twitches and bursts (p = 0.01), regardless of treatment. This general time-related weakening was more marked in IPC than SHAM at 5-Hz stimulation. No effects were observed on the magnitude of the superficial electromyographic signal.

conclusionData indicate that IPC does not increase muscle force during electrically stimulated contractions, supporting the idea that IPC's ergogenic effects are not due to increased muscle contractility.

Indexed as

Ischemic PreconditioningIsometric ContractionMuscle ContractionMuscle, SkeletalAdultElectric StimulationFemaleHumansMaleElectrically stimulated contractionElectromyographicForceHemodynamic variablesIschemic pre-conditioning

Identifiers

PMID39168899
PMCPMC11747073

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.