Evidence map›Paper›PMID 39168891›Full record

Observational studyEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2024

Prolonged opioid use after single-level lumbar spinal fusion surgery in a Belgian population: a multicentric observational study.

Vincent Raymaekers, Gert Roosen, Eric Put, Salah-Eddine Achahbar, Sacha Meeuws, Maarten Wissels, Sven Bamps, Steven Vanvolsem, Dirk De Ridder, Tomas Menovsky and 1 more

Erratum issuedAbstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Vincent RaymaekersDepartment of Neurosurgery, Antwerp University Hospital, Antwerp, Belgium.
Gert RoosenDepartment of Neurosurgery Jessa Hospital, Hasselt, Belgium.
Eric PutDepartment of Neurosurgery Jessa Hospital, Hasselt, Belgium.
Salah-Eddine AchahbarDepartment of Neurosurgery Jessa Hospital, Hasselt, Belgium.
Sacha MeeuwsDepartment of Neurosurgery Jessa Hospital, Hasselt, Belgium.
Maarten WisselsDepartment of Neurosurgery Jessa Hospital, Hasselt, Belgium.
Sven BampsDepartment of Neurosurgery Jessa Hospital, Hasselt, Belgium.
Steven VanvolsemDepartment of Neurosurgery Jessa Hospital, Hasselt, Belgium.
Dirk De RidderDepartment of Surgical Sciences, Section of Neurosurgery, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.
Tomas MenovskyDepartment of Neurosurgery, Antwerp University Hospital, Antwerp, Belgium.
Mark PlazierFaculty of Medicine and Life Science, Hasselt University, Hasselt, Belgium.

Funding

Medtronic Europe NM-3422
6 · The paper itself

Abstract

purposeLumbar spinal fusion surgeries are increasingly being performed in spinal degenerative disease, often accompanied by perioperative opioid prescriptions. The aim of this study is to analyze prolonged postoperative opioid use following a standardized opioid prescription after single-level lumbar spinal fusion surgery in a Belgian population.

methodsThis prospective, multicentric observational study included patients undergoing single-level lumbar fusion surgery for degenerative disease. A standardized postoperative opioid protocol (Targinact 2 × 10 mg/5 mg, Paracetamol 4 × 1 g and Ibuprofen 3 × 600 mg) was applied uniformly. Prolonged opioid use was defined as continued opioid use six months after surgery. Patient data were collected using the Back-App

resultsAmong 198 participants, 32.8% continued opioid use six months post-surgery, with 8% utilizing strong opioids. Prolonged opioid use correlated with lower pre-operative back pain. Patients with prolonged opioid use and strong opioid use at six months show less improvement in disability compared to patients without prolonged opioid use. Moreover, patients with prolonged strong opioid use tend to have lesser improvement of the low back pain. The odds for prolonged opioid use decrease with the increase of the improvement in ODI.

conclusion1 in 3 patients undergoing single-level lumbar spinal fusion surgery is at risk for prolonged opioid use. The study underscores the importance of tailored pain management strategies, particularly given the rising prevalence of spinal fusion surgeries. The association between pre-operative low back pain, post-operative improvement in functionality (ODI), and prolonged opioid use emphasizes the need for judicious opioid prescribing practices and highlights the role of functional outcomes in treatment goals.

Indexed as

Analgesics, OpioidLumbar VertebraePostoperative PainSpinal FusionAdultAgedBelgiumFemaleHumansLow Back PainMaleMiddle AgedProspective StudiesAnalgesics, OpioidChronic opioid useLow back painLumbar spinal fusionOswestry Disability Index (ODI)Patient-reported outcomes (PROMs)PLIFPostoperative outcomesQuality of life (QOL)Real-world evidenceRisk factors

Identifiers

PMID39168891

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.