Evidence map›Paper›PMID 39168501›Full record

ArticlePediatric dermatology

Diagnostic challenge: Juvenile bullous pemphigoid with a negative BP180 ELISA.

Janet A Fairley, Kristen G Berrebi, Andrew M Poggemiller, Afshin Varzavand, Kelly N Messingham

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Janet A FairleyDepartment of Dermatology, The University of Iowa Health Care Medical Center, Iowa City, Iowa, USA.ORCID https://orcid.org/0000-0002-8203-0486
Kristen G BerrebiDepartment of Dermatology, The University of Iowa Health Care Medical Center, Iowa City, Iowa, USA.ORCID https://orcid.org/0000-0001-8537-3647
Andrew M PoggemillerDepartment of Dermatology, The University of Iowa Health Care Medical Center, Iowa City, Iowa, USA.ORCID https://orcid.org/0000-0001-5235-7798
Afshin VarzavandDepartment of Dermatology, The University of Iowa Health Care Medical Center, Iowa City, Iowa, USA.ORCID https://orcid.org/0000-0001-7137-6580
Kelly N MessinghamDepartment of Dermatology, The University of Iowa Health Care Medical Center, Iowa City, Iowa, USA.ORCID https://orcid.org/0000-0003-4630-0722

Funding

University of Iowa Department of Dermatology
6 · The paper itself

Abstract

Bullous pemphigoid (BP) is an autoimmune blistering disease primarily affecting the elderly, whereas cases of juvenile BP are rare. Both types of BP are typically mediated by autoantibodies targeting the NC16A region of BP180; however, a small subset of adult patient sera react to other regions of the protein. The incidence of a similar occurrence in juvenile BP is unknown. This case of juvenile BP with a negative BP180 ELISA highlights diagnostic pitfalls that can lead to a delay in the correct diagnosis in the pediatric population.

Indexed as

AutoantibodiesAutoantigensNon-Fibrillar CollagensPemphigoid, BullousChildCollagen Type XVIIEnzyme-Linked Immunosorbent AssayFemaleHumansMaleAutoantibodiesAutoantigensCollagen Type XVIINon-Fibrillar Collagensautoantibodiesbullous pemphigoidcollagen type VIIELISApediatric

Identifiers

PMID39168501
PMCPMC11950797

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.